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Polylactic acid reinforced with nano-hydroxyapatite bioabsorbable cortical screws for bone fracture treatment

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Abstract

Bioabsorbable polymers are an alternative to the metal as an implant to avoid stress shielding, corrosion, and revision surgeries. So, the current work aimed to develop the cortical screw implants with polylactic acid (PLA) and nano-Hydroxyapatite (nHAp) to treat fractures. For this purpose, nHAp reinforced PLA cortical screws were made by the injection moulding technique. The optimum ratio of nHAp and PLA resulted in an axial pull-out strength of 737 N, an improvement of ~ 37% compared to pristine PLA. The torsional, flexural, and shear strength of the PLA/nHAp screws were 1157 mNm, 100 N and 49 MPa, respectively. Compared to neat PLA, an improvement of 30%, 23%, and 12% was witnessed in torsional, flexural, and shear strength. In-vitro hydrolytic degradation studies showed 14% and 10% mass reduction after 90 days for neat PLA and PLA/nHAp. The results obtained from the present investigation indicated the promising nature of the developed biocomposite internal fixation devices for bone fracture treatment.

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All data associated with this study is provided in the manuscript.

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Acknowledgements

The authors sincerely acknowledge the Centre of Excellence for Sustainable Polymers (CoE-SusPol) at the Indian Institute of Technology Guwahati, Central Workshop, IIT Guwahati, and Central Instrumentation Facility, IIT Guwahati, for providing the necessary facilities to execute this research work.

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Authors and Affiliations

  1. Department of Mechanical Engineering, Indian Institute of Technology Guwahati, North Guwahti, Assam, India

    Arbind Prasad

  2. Department of Chemical Engineering, Indian Institute of Technology Guwahati, North Guwahati, Assam, India

    Siddharth Mohan Bhasney & Vimal Katiyar

  3. Centre for Sustainable Polymers, Indian Institute of Technology Guwahati, North Guwahati, Assam, India

    Varatharajan Prasannavenkadesan & Vimal Katiyar

  4. Department of Mechanical Engineering, Indian Institute of Technology Tirupati, Tirupati, Andhra Pradesh, India

    Mamilla Ravi Sankar

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Correspondence to Vimal Katiyar.

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Prasad, A., Bhasney, S.M., Prasannavenkadesan, V. et al. Polylactic acid reinforced with nano-hydroxyapatite bioabsorbable cortical screws for bone fracture treatment. J Polym Res 30, 177 (2023). https://doi.org/10.1007/s10965-023-03542-8

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