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Improvement in antibacterial activity of Poly Vinyl Pyrrolidone/Chitosan incorporated by graphene oxide NPs via laser ablation

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Abstract

Laser ablation was used to create novel nanocomposites of Chitosan-Poly (Vinyl Pyrrolidone) (PVP) blend incorporating graphene oxide nanoparticles (GONPs) to be utilized in microbial applications. The change in the structural, and optical properties of pure Chitosan-PVP after incorporated by graphene oxide have been investigated. XRD results confirmed the incorporation of GO into Chitosan/PVP blend and FT-IR results confirmed the interaction between Chitosan-PVP and GO NPs. UV data was confirmed that Chitosan/PVP/GO NPs after laser ablation time 10 min has lower band gap energy compared to other samples. The antimicrobial behavior of Chitosan/PVP/GO NPs at two times of laser ablation (5 min and 10 min) were performed against E. coli, P. aeruginosa, S. aureus, B. subtilis, and C. Albicans. The antimicrobial activity shows enhancement in the inhibition zones, it was enhanced from 5 ± 0.98 to 13 ± 0.72 for E. coli, 6 ± 0.56to 15 ± 0.84 for P. aeruginosa, 7 ± 0.73 to 17 ± 0.26 for S. aureus, 4 ± 0.89 to 15 ± .07 for B. subtilis, and 3 ± 0.54 to 8 ± 0.76 for C. Albicans. Chitosan/PVP/GO NPs significantly improve antimicrobial effects. The prepared compositions could be suggested after further study to be applied in microbial applications.

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Acknowledgements

This research has been funded by Scientific Research Deanship at University of Ha'il–Saudi Arabia through project number RG-20-211.

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Authors and Affiliations

  1. Medical Laboratory Sciences Department, College of Applied Medical Sciences, Ha’il University, Ha’il, Saudi Arabia

    Mohammed S. Al Mogbel

  2. Public Health Department, College of Public Health and Health Informatics, Ha’il University, Ha’il, Saudi Arabia

    Mohamed T. Elabbasy

  3. Food Control Department, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt

    Mohamed T. Elabbasy

  4. Department of Agricultural Microbiology, Faculty of Agriculture, Cairo University, Cairo, 12613, Egypt

    Rasha S. Mohamed

  5. Department of Botany, Faculty of Agriculture, Cairo University, Giza, Egypt

    A. E. Ghoniem

  6. Biophysics Department, Faculty of Science, Cairo University, Giza, Egypt

    M. F. H. Abd El-Kader

  7. Basic Sciences Department, Deanship of Preparatory Year, Ha’il University, Ha’il, Saudi Arabia

    M. F. H. Abd El-Kader

  8. Laser Technology Unit, Center of Excellent for Advanced Science, National Research Centre, Dokki, Giza, 12622, Egypt

    A. A. Menazea

  9. Spectroscopy Department, Physics Research Institute, National Research Centre, Dokki, Giza, 12622, Egypt

    A. A. Menazea

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  1. Mohammed S. Al Mogbel
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Al Mogbel, M.S., Elabbasy, M.T., Mohamed, R.S. et al. Improvement in antibacterial activity of Poly Vinyl Pyrrolidone/Chitosan incorporated by graphene oxide NPs via laser ablation. J Polym Res 28, 474 (2021). https://doi.org/10.1007/s10965-021-02838-x

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