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Biomodulation of poly (vinyl alcohol)/starch polymers into composite-based hybridised films: physico-chemical, structural and biocompatibility characterization

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Abstract

The aim of present research work was to bio-modulate Poly (vinyl alcohol)/Starch (PVA/S) polymers and synthesize composite-based PVA/S hybridised films incorporated with ZnO, TiO2 and gelatin protein hydrolysate (GPH) components. The prepared PVA/S based composite hybridised films were characterized for physico-chemical, thermal and structural characterisation using Fourier transform infrared spectroscopy (FTIR), Scanning electron microscopy (SEM), Thermal gravity analysis (TGA), and X-ray diffraction (XRD) analyses. Notably, the incorporation of composites has made certain physico- chemical and structural modifications but not altered the molecular structure of biopolymer as revealed by FTIR analysis. The gelatinized blends of PVA/S based hybridised composite films incorporated with ZnO, TiO2 and GPH components have shown better thermal stability and miscibility as revealed by thermal gravity analysis. The biocompatibility was investigated by evaluating viability of L929 fibroblast cell, which had good biocompatibility and was non-toxic in nature. These PVA/S based composite hybridised films could be implemented in therapeutic biomedical research and food industrial applications.

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Acknowledgements

The authors would like to express their sincere gratitude to ICAR for providing funds to carry out the research work under ICAR-National Fellow Scheme. The authors acknowledge Director, ICAR-Central Institute of Fisheries Technology (ICAR-CIFT), Cochin, Kerala, India for providing the facilities to carry out this work and also for granting permission to publish the data acquired from the study. The authors are grateful to Mrs. P. A. Jaya (Technical Officer), Mr. P. Suresh (Senior Technician), Mrs. N. Lekha (Technical Officer) ICAR-Central Institute of Fisheries Technology (CIFT), Cochin, Kerala for providing technical support to carry out the analyses.

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Authors and Affiliations

  1. Biochemistry and Nutrition Division, ICAR- Central Institute of Fisheries Technology, Cochin, 682029, Kerala, India

    Pavan Kumar Dara, Mahadevan R., Anandan Rangasamy, Suseela Mathew & Ravishankar C. N.

  2. Microbiology and Biotechnology Division, ICAR- Central Institute of Fisheries Technology, Cochin, 682029, Kerala, India

    Sivaraman G. K. & Visnuvinayagam S.

  3. Chimertech Innovations LLP, Veterinary Incubation Foundation@ TANUVAS CUL Building, Madhavaram Milk Colony, Chennai - 600 051, Tamil Nadu, India

    Karthik Deekonda

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  1. Pavan Kumar Dara
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  2. Mahadevan R.
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  3. Sivaraman G. K.
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  5. Visnuvinayagam S.
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  8. Ravishankar C. N.
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Correspondence to Anandan Rangasamy.

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Dara, P.K., R., M., G. K., S. et al. Biomodulation of poly (vinyl alcohol)/starch polymers into composite-based hybridised films: physico-chemical, structural and biocompatibility characterization. J Polym Res 28, 265 (2021). https://doi.org/10.1007/s10965-021-02578-y

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