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Preparation and controlled properties of temperature/photo dual sensitive polymers by facile Ugi reaction

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Abstract

In this investigation, we described a facile preparation of temperature/photo dual sensitive polymers (PGABs) by Ugi four-component polymerization (Ugi-4CP) at room temperature in “one-pot” method using glutaraldehyde, 4-amido-azobenzene, t-butyl isocyanide and carboxyl-end-capped polyethylene glycols (S-PEG) as monomers. PGABs were found to be reversibly sensitive to the temperature in salt solution, and their lower critical solution temperatures (LCST) can be tuned to the range of 17.2–68.4 °C by changing the structure of PGABs, sort and concentration of salt. The configuration transition of PGABs between cis-form and trans-form was reversibly induced by the alternating radiation at 365 and 254 nm. The rate and conversion of isomerization showed a remarkable dependence on the chemical structure of PGAB. By the photosensitivity, the LCST of PGAB-800 is further regulated in 1.0 °C change because of the hydrophilicity difference of cis-trans-azobenzene moiety. Through the combination of the thermosensitivity and photosensitivity, the particles of PGABs with nano/μm dimension were successfully controlled by the light radiation and temperature change.

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Authors and Affiliations

  1. College of Chemistry & Environmental Science, Affiliated Hospital, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis (Ministry of Education), Hebei University, Baoding, 071002, China

    Congcong Fu, Lan Ding, Jialin Yin, Shasha Tian, Lan Ma, Qi Zhang, Fei Qin, Lili Cao & Kuilin Deng

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  1. Congcong Fu
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  2. Lan Ding
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Fu, C., Ding, L., Yin, J. et al. Preparation and controlled properties of temperature/photo dual sensitive polymers by facile Ugi reaction. J Polym Res 27, 216 (2020). https://doi.org/10.1007/s10965-020-02167-5

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