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Calcium carbonate deposition on layer-by-layer systems assembled from star polymers

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Abstract

Layer-by-layer (LbL) systems constructed via electrostatic attraction or other forces can be used as templates in biomimetic mineralization. In this work, 21-arm star poly(acrylic acid) (star-PAA) and 21-arm star poly[2-(dimethylamino)ethyl methacrylate] (star-PDMAEMA) were successfully synthesized from a cyclodextrin core via atom transfer radical polymerization (ATRP). The star polymers were used to construct three kinds of LbL systems: negatively charged star-PAA with positively charged chitosan (CHI) as a model of unconfined space for mineralization, and positively charged star-PDMAEMA with negatively charged poly(styrene sulfonic acid) sodium salt (PSS), which had acid-etched holes or constructed within a porous polycarbonate filters, as two different models of confined space for mineralization. Different crystal forms of calcium carbonate were obtained using the three systems, so these LbL systems assembled from star polymers could be new tools for developing functional materials and investigating fundamental aspects of the mineralization process.

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References

  1. Mann S (2001) Biomineralization: principles and concepts in bioinorganic materials chemistry. Oxford University Press, New York

  2. Mann S (ed)(1997) Biomimetic materials chemistry. Wiley-VCH, Weinheim

  3. Lowenstam HA, Weiner S (eds)(1989) On biomineralization. Oxford University Press, Oxford

  4. Li L, Mao C, Wang J, Xu X, Pan H, Deng Y, Gu X, Tang R (2011) Bio-inspired enamel repair via Glu-directed assembly of apatite nanoparticles: an approach to biomaterials with optimal characteristics. Adv Mat 23:4395–4701

    Google Scholar 

  5. Wang T, Porter D, Shao Z (2011) The Intrinsic Ability of Silk Fibroin to Direct the Formation of Diverse Aragonite Aggregates. Adv Fun Mat 22:435–441

    Article  Google Scholar 

  6. Zhai H, Jiang W, Tao J, Lin S, Chu X, Xu X, Tang R (2010) Self-assembled organic-inorganic hybrid elastic crystal via biomimetic mineralization. Adv Mat 22:3729–3734

    Google Scholar 

  7. Sanchez C, Arribart H, Guille MMG (2005) Biomimetism and bioinspiration as tools for the design of innovative materials and systems. Nat Mat 4:277–288

    Google Scholar 

  8. Kirkham J, Firth A, Vernals D, Boden N, Robinson C, Shore RC, Brookes SJ, Aggeli A (2007) Self-assembling peptide scaffolds promote enamel remineralization. J Dent Res 86:426–430

    Google Scholar 

  9. Wu D, Yang J, Li J, Chen L, Tang B, Chen X, Wu W, Li J (2013) Hydroxyapatite-anchored dendrimer for in situ remineralization of human tooth enamel. Biomaterials 34:5036–5047

    Google Scholar 

  10. Liu Y, Li N, Qi Y, Dai L, Bryan TE, Mao J, Pashley DH, Tay FR (2011) Intrafibrillar collagen mineralization produced by biomimetic hierarchical nanoapatite assembly. Adv Mat 23:975–980

    Google Scholar 

  11. Liu Y, Kim YK, Dai L, Li N, Khan SO, Pashley DH, Tay FR (2011) Hierarchical and non-hierarchical mineralisation of collagen. Biomaterials 32:1291–1300

    Google Scholar 

  12. Kim YK, Gu L, Bryan TE, Kim JR, Chen L, Liu Y, Yoon JC, Breschi L, Pashley DH, Tay FR (2010) Mineralisation of reconstituted collagen using polyvinylphosphonic acid/polyacrylic acid templating matrix protein analogues in presence of calcium, phosphate and hydroxyl ions. Biomaterials 31:6618–6627

    Google Scholar 

  13. Gu L, Kim YK, Liu Y, Takahashi K, Arun S, Wimmer CE, Osorio R, Ling J, Looney SW, Pashley DH, Tay FR (2011) Immobilization of a phosphonated analog of matrix phosphoproteins within cross-linked collagen as a templating mechanism for biomimetic mineralization. Acta Biomater 7:268–277

    Google Scholar 

  14. Tay FR, Pashley DH (2008) Guided tissue remineralisation of partially demineralised human dentine. Biomaterials 29:1127–1137

    Google Scholar 

  15. Loste E, Park RJ, Warren J, Meldrum FC (2004) Precipitation of calcium carbonate in confinement. Adv Fun Mat 14:1211–1220

    Google Scholar 

  16. He Q, Mohwald H, Li J (2009) Layer-by-layer assembled nanotubes as biomimetic nanoreactors for calcium carbonate deposition. Macromol Rapid Comm 30:1538–1542

    Google Scholar 

  17. Adbelkebir K, Morin-Grognet S, Gaudière F, Coquerel G, Labat B, Atmani H, Ladam G (2012) Biomimetic layer-by-layer templates for calcium phosphate biomineralization. Acta Biomater 8:3419–3428

    Google Scholar 

  18. Fukui Y, Fujimoto K (2011) Control in mineralization by the polysaccharide-coated liposome via the counter-diffusion of ions. Chem Mat 23:4701–4708

    Google Scholar 

  19. Sun Q, Murase T, Sato S, Fujita M (2011) A sphere-in-sphere complex by orthogonal self-assembly. Angew Chem Int Ed 50:10318–10321

    Google Scholar 

  20. Ashley CE, Carnes EC, Phillips GK, Padilla D, Durfee PN, Brown PA, Hanna TN, Liu J, Phillils B, Carter MB, Carroll NJ, Jiang X, Dunphy DR, Willman CL, Petsev DN, Evans DG, Parikh AN, Chackerian B, Wharton W, Peabody DS, Brinker CJ (2011) The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers. Nat Mat 10:389–397

    Google Scholar 

  21. de Villiers MM, Otto DP, Strydom SJ, Lvov YM (2011) Introduction to nanocoatings produced by layer-by-layer (LbL) self-assembly. Adv Drug Deliver Rev 63:701–715

  22. Becker AL, Johnston APR, Caruso F (2010) Layer-by-layer-assembled capsules and films for therapeutic delivery. Small 6:1836–1852

    Google Scholar 

  23. Wang C, Liu H, Gao Q, Liu X, Tong Z (2007) Facile fabrication of hybrid colloidosomes with alginate gel cores and shells of porous CaCO3 microparticles. Chem Phys Chem 8:1157–1160

    Google Scholar 

  24. Zhao Y, Liu L, Lu Y, Chen S, Dong L, Yu S (2010) Templating synthesis of preloaded doxorubicin in hollow mesoporous silica nanospheres for biomedical applications. Adv Mat 22:5255–5259

    Google Scholar 

  25. Xiu K, Yang J, Zhao N, Li J, Xu F (2013) Multiarm cationic star polymers by atom transfer radical polymerization from β-cyclodextrin cores: influence of arm number and length on gene delivery. Acta biomater 9:4726–4733

    Google Scholar 

  26. Wang J, Yin C, Tang G, Lin X, Wu Q (2013) Glucose-functionalized multidrug-conjugating nanoparticles based on amphiphilic terpolymer with enhanced anti-tumorous cell cytotoxicity. Int J Pharm 441:291–298

    Google Scholar 

  27. Rezaei S, Nabid M, Niknejad H, Entezami A (2012) Folate-decorated thermoresponsive micelles based on star-shaped amphiphilic block copolymer for efficient intracellular release of anticancer drugs. Int J Pharm 437:70–79

    Google Scholar 

  28. Lu X, Gao H, Li C, Yang Y, Wang Y, Fan Y, Wu G, Ma J (2012) Polyelectrolyte complex nanoparticles of amino Poly(glycerol methacrylate)s and insulin. Int J Pharm 423:195–201

    Google Scholar 

  29. Li J, Yang J, Xu F, Xu J, Yan D, Chen C, Li J (2012) A facile strategy to modulate the fluorescent properties of star polymers by varying the arm numbers. J Polym Res 19:9941–9944

    Google Scholar 

  30. Luo ZH, Xia BR, Fu ZF (2011) Synthesis of star-shaped polymers by coupling reaction between multifunctional core and terminal functionalized polymers. J Polym Res 18:1983–1990

    Google Scholar 

  31. Miao Q, Jin Y, Dong Y, Cao ZF, Zhang BA (2010) Surface behavior and micelle morphology of novel nonionic polyurethane bolaform amphiphilic block copolymers. J Polym Res 17:911–921

    Google Scholar 

  32. Connal LA, Li Q, Quinn JF, Tjipto E, Caruso F, Qiao GG (2008) pH-responsive poly(acrylic acid) core cross-linked star polymers: morphology transitions in solution and multilayer thin films. Macromolecules 41:2620–2626

    Google Scholar 

  33. Kim BS, Gao H, Argun AA, Matyjaszewski K, Hammond PT (2009) All-star polymer multilayers as pH-responsive nanofilms. Macromolecules 42:368–375

    Google Scholar 

  34. Ramos AP, Espimpolo DM, Zaniquelli MED (2012) Influence of the type of phospholipid head and of the conformation of the polyelectrolyte on the growth of calcium carbonate thin films on LB/LbL matrices. Colloid Surface B 95:178–185

    Google Scholar 

  35. Chen X, Wu W, Guo Z, Xin J, Li J (2011) Controlled insulin release from glucose-sensitive self-assembled multilayer films based on 21-arm star polymer. Biomaterials 32:1795–1766

    Google Scholar 

  36. Yang Y, He Q, Duan L, Cui Y, Li J (2007) Assembled alginate/chitosan nanotubes for biological application. Biomaterials 28:3083–3090

    Google Scholar 

  37. Luo J, Cao S, Chen X, Liu S, Tan H, Wu W, Li J (2012) Super long-term glycemic control in diabetic rats by glucose-sensitive LbL films constructed of supramolecular insulin assembly. Biomaterials 33:8733–8742

    Google Scholar 

  38. Li J, Xiao H (2005) An efficient synthetic-route to prepare [2,3,6-tri-O-(2-bromo-2-methylpropionyl)]-β-cyclodextrin. Tetrahedron Lett 46:2227–2229

    Google Scholar 

  39. Guo Z, Chen X, Zhang X, Xin J, Li J, Xiao H (2010) Effective syntheses of per-2,3-di- and per-3-O-chloroacetyl-β-cyclodextrins: a new kind of ATRP initiators for star polymers. Tetrahedron Lett 51:2351–2353

    Google Scholar 

  40. Chen F, Li C, Wang X, Liu G, Zhang G (2012) pH and ion-species sensitive fluorescence properties of star polyelectrolytes containing a triphenylene core. Soft Matter 8:6364

    Google Scholar 

  41. Guo Z, Chen X, Xin J, Wu D, Li J, Xu C (2010) Effect of molecular weight and arm number on the growth and pH-dependent morphology of star poly[2-(dimethylamino)ethyl methacrylate]/poly(styrenesulfonate) multilayer Films. Macromolecules 43:9087–9093

    Google Scholar 

  42. Xu FJ, Yang WT (2011) Polymer vectors via controlled/living radical polymerization for gene delivery. Prog Polym Sci 36:1099–1131

    Google Scholar 

  43. Feng X, Pan C (2001) Synthesis and characterization of star polymers initiated by hexafunctional discotic initiator through atom transfer radical polymerization. J Polym Sci Part A 39:2233–2243

    Google Scholar 

  44. Sun H, Gao Z, Yang L, Gao L, Lv X (2010) Synthesis and characterization of novel four-arm star PDMAEMA-stabilized colloidal silver nanoparticles. Colloid Polym Sci 288:1713–1722

    Google Scholar 

  45. Zhang X, Xia J, Matyjaszewski K (1998) Controlled/“living” radical polymerization of 2-(dimethylamino)ethyl methacrylate. Macromolecules 31:5167–5169

    Google Scholar 

  46. Mao B, Gan L, Gan Y, Li X, Ravi P, Tam KC (2004) Controlled polymerizations of 2-(dialkylamino)ethyl methacrylates and their block copolymers in protic solvents at ambient temperature via ATRP. J Polym Sci Part A 42:5156–5169

    Google Scholar 

  47. Mao B, Gan L, Gan Y (2006) Ultra high molar mass poly[2-(dimethylamino)ethyl methacrylate] via atom transfer radical polymerization. Polymer 47:3017–3020

    Google Scholar 

  48. Kitamura M, Konno H, Yasui A, Masuoka H (2002) Controlling factors and mechanism of reactive crystallization of calcium carbonate polymorphs from calcium hydroxide suspensions. J Cryst Growth 236:323–332

    Google Scholar 

  49. Matsumoto M, Fukunaga T, Onoe K (2010) Polymorph control of calcium carbonate by reactive crystallization using microbubble technique. Chem Eng Res Des 88:1624–1630

    Google Scholar 

  50. Srivastava P, Bhattacharyya T, Pal DK (2002) Significance of the formation of calcium carbonate minerals in the pedogenesis and management of cracking clay soils (vertisols) of India. 50: 111–126

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Funding sources

Financial support from the National Natural Science Foundation of China (51073102), the Fok Ying Tung Education Foundation (122034), the Program for New Century Excellent Talents in University (NCET-10-0592), the Program for Changjiang Scholars and Innovative Research Team in University (IRT1163), Foundations of Sichuan Province (2012JQ0009), Fundamental Research Funds for the Central Universities (2010SCU22001, 2011SCU04A04) and the Natural Science Foundation of Jiangsu Province (BK2010248, BK2011340) is gratefully acknowledged.

Notes

The authors declare that they have no competing financial interests.

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Authors and Affiliations

  1. College of Polymer Science and Engineering, Sichuan University, Chengdu, 610065, China

    Jiaojiao Yang, Shuqin Cao, Jianyu Xin, Xingyu Chen, Wei Wu & Jianshu Li

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  1. Jiaojiao Yang
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  2. Shuqin Cao
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Correspondence to Jianshu Li.

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Yang, J., Cao, S., Xin, J. et al. Calcium carbonate deposition on layer-by-layer systems assembled from star polymers. J Polym Res 20, 157 (2013). https://doi.org/10.1007/s10965-013-0157-x

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