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Antibacterial effect of thiocyanate substituted poly(vinyl chloride)

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Abstract

Poly(vinyl chloride) (PVC) modified in different solvents by nucleophilic substitution with thiocyanate was exposed to Gram-negative bacteria of the strain Staphylococcus capitis. All modified pieces reduced the adhesion of bacteria by between 67 and 79%. More important for the bacteria suppression than the substitution rate was the ratio between thiocyanate and isothiocyanate groups. The best result was obtained with PVC modified in tetrahydrofuran/dimethylsulfoxide, containing only antibacterial active isothiocyanate groups, while inactive thiocyanate groups were absent.

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Authors and Affiliations

  1. Graduate School of Environmental Studies, Tohoku University, 6-6-07 Aoba, Aramaki, Aoba-ku, Sendai, 980-8579, Japan

    Tomohito Kameda, Masahiko Ono, Guido Grause, Tadaaki Mizoguchi & Toshiaki Yoshioka

Authors
  1. Tomohito Kameda
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  2. Masahiko Ono
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  3. Guido Grause
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  4. Tadaaki Mizoguchi
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  5. Toshiaki Yoshioka
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Correspondence to Toshiaki Yoshioka.

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Kameda, T., Ono, M., Grause, G. et al. Antibacterial effect of thiocyanate substituted poly(vinyl chloride). J Polym Res 18, 945–947 (2011). https://doi.org/10.1007/s10965-010-9492-3

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  • DOI: https://doi.org/10.1007/s10965-010-9492-3

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