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In Vitro Degradation Behavior of Polyesteramide Copolymer Fiber Based on 6-Aminocaproic Acid, Adipic Acid, and 1,6-Hexane Diol

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Abstract

In this work, a kind of aliphatic biodegradable polyesteramide (PEA) copolymer based on 6-aminocaproic acid, adipic acid, and 1,6-hexane diol was synthesized by melt polycondensation method, and was characterized by 1H-NMR, FTIR and DSC. The PEA fiber was prepared by melt-spinning method. Tensile properties of the as-spun and hot-drawn fibers were also investigated. Hydrolytic degradation behavior of PEA copolymer chips and fibers were evaluated by weight loss in PBS solution with different pH value. The alkaline degradation behavior of fiber was also studied on change of diameter and surface morphology. During alkaline degradation, the PEA fiber underwent surface erosion.

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Authors and Affiliations

  1. State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, 610041, People’s Republic of China

    CaiBing Liu, ZhiYong Qian, MeiJuan Huang, ChangYang Gong, HongXin Deng, Ke Lei & AnLiang Huang

  2. College of Material Science and Engineering, Sichuan University, Chengdu, 610065, People’s Republic of China

    CaiBing Liu, WenJuan Jia, GuoTao Chao, MaLing Gou & MingJing Tu

  3. Department of Textile and Clothing, Sichuan University, Chengdu, 610065, People’s Republic of China

    YingChun Gu

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  1. CaiBing Liu
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  2. WenJuan Jia
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  3. ZhiYong Qian
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Corresponding author

Correspondence to ZhiYong Qian.

Additional information

This work was financially supported by Chinese Key Basic Research Program (2004CB518800 and 2004CB518807), and Sichuan Key Project of Science and Technology (06(05SG022-021-02)).

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Liu, C., Jia, W., Qian, Z. et al. In Vitro Degradation Behavior of Polyesteramide Copolymer Fiber Based on 6-Aminocaproic Acid, Adipic Acid, and 1,6-Hexane Diol. J Polym Res 14, 31–37 (2007). https://doi.org/10.1007/s10965-006-9077-3

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  • DOI: https://doi.org/10.1007/s10965-006-9077-3

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