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Poly[2-(hydroxyethyl methacrylate)-co-(sulfobetaine)]s hydrogels: 1. Synthesis and swelling behaviors of the 2-(hydroxyethyl methacrylate)-co-2-(vinyl-1-pyridinium propane sulfonate) hydrogels

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Abstract

A series of the 2-hydroxyethyl methacrylate/2-vinyl-l-pyridinium propane sulfonate (HEMA/VPPS) copolymeric gels have been prepared from HEMA and zwitterionic monomer VPPS of various molar ratios. The influence of the amount of VPPS in copolymeric gels on their swelling behavior in water and various saline solutions at different temperatures was investigated. Results indicate that the PHEMA hydrogels exhibit an overshooting phenomenon in their dynamic swelling behavior. The maximum overshooting value decreases with increasing temperature. The same results are also shown for the lower VPPS content HEMA/VPPS copolymeric gels. In the equilibrium swelling ratio, the PHEMA hydrogel exhibits a minimum swelling ratio at 55 °C. Then, the minimum swelling ratio disappears gradually with increasing VPPS content in HEMA/VPPS copolymeric gels. In the saline solution, the swelling ratios of HEMA/VPPS copolymeric gels increase rapidly with increasing salt concentration, for salts with a smaller ratio of charge/radius.

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References

  1. J. C. Salamone, W. Volksen, A. P. Olson and S. C. Israel, Polymer, 19, 1157 (1978).

    Article  CAS  Google Scholar 

  2. V. M. Monroy Soto and J. C. Galin, Polymer, 25, 121, 254 (1984).

    CAS  Google Scholar 

  3. D. N. Schulz, D. G. Peiffer, P. K. Agarwal, J. Larabee, Kaladas, L, Soni, B. Handwerker and R. J. Garner, Polymer, 27, 1734 (1986).

    Article  CAS  Google Scholar 

  4. J. C. Salamone, W. Volkson, S. C. Israel and D. C. Raia, Polym. Prep., ACS Div. Polym. Chem., 15, 291 (1974).

    CAS  Google Scholar 

  5. J. C. Salamone, W. Volksen, S. C. Israel, A. P. Olson, and D. C. Raia, Polymer, 18, 1058 (1977).

    Article  CAS  Google Scholar 

  6. Y. H. Bae, T. Okano and S. W. Kim, J. Polym. Sci. Polym. Phys., 28, 923 (1990).

    Article  CAS  Google Scholar 

  7. A. S. Hoffman, J. Controlled Release, 4, 213 (1986).

    CAS  Google Scholar 

  8. L. C. Dong and A. S. Hoffman, J. Controlled Release, 4, 223 (1986).

    Article  CAS  Google Scholar 

  9. T. Okano, Y. H. Bae, H. Jacobs and S. W. Kim, J. Controlled Release, 11, 255 (1990).

    Article  CAS  Google Scholar 

  10. J. Kopecek, J. Vacik and D. J. Lim, Polym. Sci., Polym., Chem. Ed., 9, 2801 (1971).

    CAS  Google Scholar 

  11. F. Alhaique, M. Marchetti, F. M. Riccieri and E. Santucci, J. Pharmacol., 33, 413 (1981).

    CAS  Google Scholar 

  12. J. Ricka and J. T. Tanaka, Macromolecules, 17, 2916 (1984).

    Article  CAS  Google Scholar 

  13. S. R. Eisenberg and A. J. Grodzinski, J. Membr. Sci., 19, 173 (1984).

    Article  CAS  Google Scholar 

  14. L. C. Kwon, Y. H. Bae, T. Okano and S. W. Kim, J. Controlled Release, 17, 149 (1991).

    Article  CAS  Google Scholar 

  15. H. Feil, Y. H. Bae, T. Feijen and S. W. Kim, J. Membr. Sci., 64, 283 (1991).

    Article  CAS  Google Scholar 

  16. R. E. S. Freitas and E. L. Cussler, Chem. Eng. Sci., 42, 97 (1987).

    CAS  Google Scholar 

  17. Y. H. Bae, T. Okano and S. W. Kim, J. Controlled Release, 9, 271 (1989).

    Article  CAS  Google Scholar 

  18. L. Y. Shieh and N. A. Peppas, J. Appl. Polym. Sci., 42, 1579 (1991).

    Article  CAS  Google Scholar 

  19. N. M. Franson and N. A. Peppas, J. Appl. Polym. Sci., 28, 1299 (1983).

    Article  CAS  Google Scholar 

  20. R. W. Korsmeyer, E. W. Meerwall and N. A. Peppas, J. Polym. Sci., Polym. Phys. Ed., 24, 409 (1986).

    CAS  Google Scholar 

  21. M. B. Huglin and J. M. Rego, Macromolecules, 24, 2556 (1991).

    Article  CAS  Google Scholar 

  22. M. B. Huglin and J. M. Rego, Polym. J., 23, 1425 (1991).

    Google Scholar 

  23. M. B Huglin and J. M. Rego, Polymer, 32, 3345 (1991).

    Google Scholar 

  24. J. P Baker, H. W. Blanch and J. M. Prausnitz, Polymer, 36, 1061 (1995).

    Article  CAS  Google Scholar 

  25. D. J. Liaw, W. F. Lee, Y. C. Whung and M. C. Lin, J. Appl. Polym. Sci., 34, 999 (1987).

    Article  CAS  Google Scholar 

  26. D. J. Liaw and W. F Lee, J. Appl. Polym. Sci., 30, 4697 (1985).

    Article  CAS  Google Scholar 

  27. W. F. Lee and C. C. Tsai, J. Appl. Polym. Sci., 52, 1447 (1994).

    CAS  Google Scholar 

  28. W. F. Lee and C. C. Tsai, J. Appl. Polym. Sci., 58, 1423 (1995).

    CAS  Google Scholar 

  29. W. F. Lee and C. C. Tsai, Polymer, 35, 2210 (1994).

    CAS  Google Scholar 

  30. W. F. Lee and C. C. Tsai, Polymer, 36, 357 (1995).

    CAS  Google Scholar 

  31. W. F. Lee and C. H. Lee, Polymer, 38, 971 (1997).

    CAS  Google Scholar 

  32. W. F. Lee and G. Y. Hwong, J. Appl. Polym. Sci., 59, 599 (1996).

    CAS  Google Scholar 

  33. W. F. Lee and G. Y. Hwong, Polymer, 37, 4389 (1996).

    CAS  Google Scholar 

  34. W. F. Lee and G. Y. Hwong, J. Appl. Polym. Sci., 60, 187 (1996).

    CAS  Google Scholar 

  35. B. G. Kabra, S. H. Gehrke, and S. T. Hwang, J. Appl. Polym. Sc., 42, 2409 (1991).

    CAS  Google Scholar 

  36. T. C. Warren and W. Prins, Macromolecules, 5, 506 (1972).

    Article  CAS  Google Scholar 

  37. P. J. Flory, Principles of Polymer Chemistry, Cornell University Press, New York, Chap. XIII, 1953.

    Google Scholar 

  38. T. Alfrey, E. F. Gurnee and W. G. Lloyd, J. Polym. Sci., C12, 249 (1966).

    Google Scholar 

  39. M. F. Refojo, J. Polym. Sci., A, 5, 3103 (1967).

    CAS  Google Scholar 

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  1. Department of Chemical Engineering, Tatung Institute of Technology, Taipei, 10451, Taiwan, ROC

    Wen-Fu Lee & Chin-Fu Chen

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  1. Wen-Fu Lee
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  2. Chin-Fu Chen
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Lee, WF., Chen, CF. Poly[2-(hydroxyethyl methacrylate)-co-(sulfobetaine)]s hydrogels: 1. Synthesis and swelling behaviors of the 2-(hydroxyethyl methacrylate)-co-2-(vinyl-1-pyridinium propane sulfonate) hydrogels. J Polym Res 5, 105–114 (1998). https://doi.org/10.1007/s10965-006-0046-7

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  • DOI: https://doi.org/10.1007/s10965-006-0046-7

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