Exposure to Violence Predicting Cortisol Response During Adolescence and Early Adulthood: Understanding Moderating Factors
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Previous research on the association between violence and biological stress regulation has been largely cross-sectional, and has also focused on childhood. Using longitudinal data from a low-income, high-risk, predominantly African-American sample (n = 266; 57 % female), we tested hypotheses about the influence of cumulative exposure to violence during adolescence and early adulthood on cortisol responses in early adulthood. We found that cumulative exposure to violence predicted an attenuated cortisol response. Further, we tested whether sex, mothers’ support, or fathers’ support moderated the effect of exposure to violence on cortisol responses. We found that the effect of cumulative exposure to violence on cortisol was modified by sex; specifically, males exposed to violence exhibited a more attenuated response pattern. In addition, the effect of cumulative exposure to violence on cortisol was moderated by the presence of fathers’ support during adolescence. The findings contribute to a better understanding of how cumulative exposure to violence influences biological outcomes, emphasizing the need to understand sex and parental support as moderators of risk.
KeywordsContextual stressors Violence exposure Stress response Cortisol Adolescence
This research was funded by the National Institute on Drug Abuse, Grant Number DA007484. The research reported here does not necessarily reflect the views or policies of the National Institute on Drug Abuse. The research reported here was also supported by the Michigan Youth Violence Prevention Center, Cooperative Agreement Number 5U01CE001957-02 from the Centers for Disease Control and Prevention, and the Michigan Injury Center, Grant Number 1R49CE002099. The research reported here does not necessarily represent the official position of the Centers for Disease Control and Prevention. Finally, the authors would like to acknowledge Benjamin Zimmerman, who provided research assistance on the project.
Conflict of interest
The authors declare that they have no conflict of interest.
SMA conceived of, designed, and coordinated the study. SMA also drafted the manuscript and contributed to the statistical analyses and interpretation of the data. JEH assisted with the conception and design of the study, performed the statistical analysis, and assisted with interpretation of the data. JEH also assisted with revising the manuscript. ALM assisted with the study design and also helped with drafting the manuscript. SAS and MAZ contributed to the conception of the study and reviewed the manuscript. Finally, all authors read and approved of the final manuscript. The authors on the manuscript have agreed to the byline order and to submission of the manuscript in this form.
- Brenner, A. B., Zimmerman, M. A., Bauermeister, J. A., & Caldwell, C. H. (2012). The physiological expression of living in disadvantaged neighborhoods for youth. Journal of Youth and Adolescence, 1–15. doi: 10.1007/s10964-012-9838-8. NIHMSID: NIHMS416568.
- Cabrera, N., Tamis-LeMonda, C. S., Bradley, R. H., Hofferth, S., & Lamb, M. E. (2000). Fatherhood in the twenty-first century. Child Development, 71, 27–136.Google Scholar
- Cohen, S., Hamrick, N. M., Rodriguez, M. S., Feldman, P. J., Rabin, B. S., & Manuck, S. B. (2000). The stability of and intercorrelations among cardiovascular, immune, endocrine, and psychological reactivity. Annals of Behavioral Medicine, 22, 171–179. doi: 10.1007/BF02895111.PubMedCrossRefGoogle Scholar
- Collins, W. A., & Steinberg, L. (2006). Adolescent development in interpersonal context. In W. Damon & N. Eisenberg (Eds.), Handbook of child psychology: Socioemotional processes (Vol. 4, pp. 1003–1067). New York: Wiley.Google Scholar
- Compas, B. E., Howell, D. C., Phares, V., Williams, R. A., & Ledoux, N. (1989). Parent and child stress and symptoms: An integrative analysis. Developmental Psychology, 25, 550–559.Google Scholar
- D’angiulli, A., Van Roon, P. M., Weinberg, J., Oberlander, T. F., Grunau, R. E., Hertzman, C., et al. (2012). Frontal EEG/ERP correlates of attentional processes, cortisol and motivational states in adolescents from lower and higher socioeconomic status. Frontiers in Human Neuroscience, 6, 306. doi: 10.3389/fnhum.2012.00306.PubMedCentralPubMedGoogle Scholar
- Dozier, M., Peloso, E., Lewis, E., Laurenceau, J. P., & Levine, S. (2008). Effects of an attachment-based intervention on the cortisol production of infants and toddlers in foster care. Development and Psychopathology. Special Issue: Integrating Biological Measures into the Design and Evaluation of Prevention Interventions, 20, 845–859. doi: 10.1017/S0954579408000400.Google Scholar
- Dulin-Keita, A., Casazza, K., Fernandez, J. R., Goran, M. I., & Gower, B. (2010). Do neighborhoods matter? Neighborhood disorder and long-term trends in serum cortisol levels. Journal of Epidemiology and Community Health, 66, 24–29. doi: 10.1136/jech.2009.092676.PubMedCentralPubMedCrossRefGoogle Scholar
- Fairchild, G., van Goozen, S. H., Stollery, S. J., Brown, J., Gardiner, J., Herbert, J., et al. (2008). Cortisol diurnal rhythm and stress reactivity in male adolescents with early-onset or adolescence-onset conduct disorder. Biological Psychiatry, 64, 599–606. doi: 10.1016/j.biopsych.2008.05.022.PubMedCentralPubMedCrossRefGoogle Scholar
- Graber, J. A., & Sontag, L. M. (2009). Internalizing problems during adolescence. In R. M. Lerner & L. Steinberg (Eds.), Handbook of adolescent psychology: Individual bases of adolescent development (3rd ed., Vol. 1). New Jersey: Wiley.Google Scholar
- Hankin, B. L., Badanes, L. A., Abela, J. R., & Watamura, S. E. (2010). Hypothalamic–pituitary–adrenal axis dysregulation in dysphoric children and adolescents: Cortisol reactivity to psychosocial stress from preschool through middle adolescence. Biological Psychiatry, 68, 484–490. doi: 10.1016/j.biopsych.2010.04.004.PubMedCentralPubMedCrossRefGoogle Scholar
- Klimes-Dougan, B., Hastings, P. D., Granger, D. A., Usher, B. A., & Zahn-Waxler, C. (2001). Adrenocortical activity in at-risk and normally developing adolescents: Individual differences in salivary cortisol basal levels, diurnal variation, and responses to social challenges. Development and Psychopathology, 13, 695–719.PubMedCrossRefGoogle Scholar
- Lamb, M. E., & Tamis-Lemonda, C. S. (2004). The role of the father: An introduction. In M. E. Lamb (Ed.), The role of the father in child development (4th ed., pp. 1–31). New York: John Wiley & Sons.Google Scholar
- Latkin, C. A., & Curry, A. D. (2003). Stressful neighborhoods and depression: A prospective study of the impact of neighborhood disorder. Journal of Health and Social Behavior, 34–44.Google Scholar
- Macpherson, L., Reynolds, E. K., Daughters, S. B., Wang, F., Cassidy, J., Mayes, L. C., et al. (2010). Positive and negative reinforcement underlying risk behavior in early adolescents. Prevention Science, 11, 331–342. doi: 10.1007/s11121-010-0172-7.
- Natsuaki, M. N., Klimes-Dougan, B., Ge, X., Shirtcliff, E. A., Hastings, P. D., & Zahn-Waxler, C. (2009). Early pubertal maturation and internalizing problems in adolescence: Sex differences in the role of cortisol reactivity to interpersonal stress. Journal of Clinical Child & Adolescent Psychology, 38, 513–524. doi: 10.1080/15374410902976320.CrossRefGoogle Scholar
- Procidano, M. E., & Heller, K. (1983). Measures of perceived social support from friends and from family: Three validation studies. American Journal of Community Psychology, 11, 1–24.Google Scholar
- Rao, U., Hammen, C., Ortiz, L. R., Chen, L. A., & Poland, R. E. (2008). Effects of early and recent adverse experiences on adrenal response to psychosocial stress in depressed adolescents. Biological Psychiatry, 64, 521–526. doi: 10.1016/j.biopsych.2008.05.012.PubMedCentralPubMedCrossRefGoogle Scholar
- Shih, J. H., Eberhart, N. K., Hammen, C. L., & Brennan, P. A. (2006). Differential exposure and reactivity to interpersonal stress predict sex differences in adolescent depression. Journal of Clinical Child and Adolescent Psychology, 35, 103–115. doi: 10.1207/s15374424jccp3501_9.PubMedCrossRefGoogle Scholar
- Smith, B. W., Ortiz, J. A., Steffen, L. E., Tooley, E. M., Wiggins, K. T., Yeater, E. A., et al. (2011). Mindfulness is associated with fewer PTSD symptoms, depressive symptoms, physical symptoms, and alcohol problems in urban firefighters. Journal of Consulting and Clinical Psychology, 79, 613–617. doi: 10.1037/a0025189.PubMedCrossRefGoogle Scholar
- Susman, E. J., & Dorn, L. D. (2009). Puberty: Its role in development. In R. M. Lerner & L. Steinberg (Eds.), Handbook of adolescent psychology (pp. 116–151). New York: John Wiley & Sons.Google Scholar
- Tops, M., Boksem, M. A., Wester, A. E., Lorist, M. M., & Meijman, T. F. (2006). Task engagement and the relationships between the error-related negativity, agreeableness, behavioral shame proneness and cortisol. Psychoneuroendocrinology, 31, 847–858. doi: 10.1016/j.psyneuen.2006.04.001.PubMedCrossRefGoogle Scholar
- United States Bureau of Labor Statistics. (2013). Economy at a Glance: Flint, Michigan. http://www.bls.gov/eag/eag.mi_flint_msa.htm.
- U.S. Department of Justice-Federal Bureau of Investigation. (2012). Uniform Crime Report: Crime in the United States, 2011.Google Scholar
- Walker, E., Trotman, H., Brasfield, J., Esterberg, M., & Larsen, M. (2011). Stress hormones, genes, and neuronal signaling in adolescence. The perfect storm for vulnerability to psychosis. The dynamic genome and mental health: The role of genes and environments in youth development. New York: Oxford University Press, Inc.Google Scholar
- Zahr, L. K. (1996). Effects of war on the behaviour of Lebanese pre-school children: The influence of home environment and family functioning. American Journal of Orthopsychiatry, 66, 401–408.Google Scholar