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“While a Storm is Raging on the Open Sea”: Regional Development in a Knowledge-based Economy

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Abstract

The Triple Helix of university–industry–government (UIG) relations is elaborated into a systemic model that accounts for interactions among three dimensions. By distinguishing between the respective micro-operations, this model enables us to recombine the “Mode 2” thesis of a new production of scientific knowledge and the study of systems of innovation with the neo-classical perspective on the dynamics of the market. The mutual information in three dimensions provides us with an indicator for the self-organization of the resulting network systems. The probabilistic entropy in this mutual information can be negative in knowledge-based configurations. The knowledge base of an economy can be considered as a second-order interaction effect among interactions at interfaces between institutions and functions in different spheres. Proximity enhances the chances for couplings and, therefore, the formation of technological trajectories. The next-order regime of the knowledge base, however, can be expected to remain pending as selection pressure.

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References

  • W.J. Abernathy J. Utterback (1978) ArticleTitle‘Patterns of Industrial Innovation’ Technology Review 50 41–47

    Google Scholar 

  • N. Abramson (1963) Information Theory and Coding McGraw-Hill New York

    Google Scholar 

  • M. Abramowitz (1956) ArticleTitle‘Resource and Output Trends in the United States since 1870’ American Economic Review 46 5–23

    Google Scholar 

  • M. Abramowitz P.A. David (1996) ‘Measuring Performance of Knowledge-Based Economy,’ Employment and Growth in the Knowledge-Based Economy OECD Paris 35–60

    Google Scholar 

  • M.S. Archer (1995) Realist Social Theory: The Morphogenetic Approach Cambridge University Press Cambridge, UK

    Google Scholar 

  • K.J. Arrow (1962) ArticleTitle‘The Economic Implications of Learning by Doing’ Review of Economic Studies 29 155–173

    Google Scholar 

  • W.B. Arthur (1989) ArticleTitle‘Competing Technologies, Increasing Returns, and Lock-in by Historical Events’ Economic Journal 99 116–131

    Google Scholar 

  • W.B. Arthur (1994) Increasing Returns and Path Dependence in the Economy University of Michigan Press Ann Arbor

    Google Scholar 

  • W.B. Arthur S.N. Durlauf D.A. Lane (Eds) (1997) The Economy as an Evolving Complex System II Addison-Wesley Redwood, CA

    Google Scholar 

  • R. Ashby (1958) ArticleTitle‘Requisite Variety and its Implications for the Control of Complex Systems’ Cybernetica 1 IssueID2 1–17

    Google Scholar 

  • R. Barras (1990) ArticleTitle‘Interactive Innovation in Financial and Business Services: The Vanguard of the Service Revolution’ Research Policy 19 215–237 Occurrence Handle10.1016/0048-7333(90)90037-7

    Article  Google Scholar 

  • G. Beccatini M. Bellandi G. Dei Ottati F. Sforzi (2003) From Industrial Districts to Local Development: An Itinerary of Research Edward Elgar Centenham, UK; Norhhampton, MA

    Google Scholar 

  • D. Bell (1973) The Coming of the Post-Industrial Society Basic Books New York

    Google Scholar 

  • L. Biggiero (1998) ArticleTitle‘Italian Industrial Districts: A Triple Helix Pattern of Problem Solving’ Industry and Higher Education 12 IssueID4 227–234

    Google Scholar 

  • R.A. Boschma J.G. Lambooy (2002) ArticleTitle‘Knowledge, Market Structure and Economic Coordination: The Dynamics of Italian Industrial Districts’ Growth and Change 33 IssueID3 291–311 Occurrence Handle10.1111/1468-2257.00192

    Article  Google Scholar 

  • H.-J. Braczyk P. Cooke M. Heidenreich (Eds) (1998) Regional Innovation Systems University College London Press London/ Bristol PA

    Google Scholar 

  • E. Bruckner W. Ebeling M.A.J. Montaño A. Scharnhorst (1994) Hyperselection and Innovation Described by a Stochastic Model of Technological Evolution L. Leydesdorff P. Besselaar ParticleVan den (Eds) Evolutionary Economics and Chaos Theory: New Directions in Technology Studies Pinter London 79–90

    Google Scholar 

  • M. Callon (1998) The Laws of the Market Blackwell Oxford and Malden, MA

    Google Scholar 

  • M. Callon C. Méadel V. Rabeharisoa (2002) ArticleTitle‘The Economy of Qualities’ Economy and Society 31 IssueID2 194–217 Occurrence Handle10.1080/03085140220123126

    Article  Google Scholar 

  • B. Carlsson (Eds) (2002) New Technological Systems in the Bio Industries—an International Study Kluwer Academic Publishers Boston/Dordrecht/London

    Google Scholar 

  • B. Carlsson R. Stankiewicz (1991) ArticleTitle‘On the Nature, Function, and Composition of Technological Systems’ Journal of Evolutionary Economics 1 IssueID2 93–118 Occurrence Handle10.1007/BF01224915

    Article  Google Scholar 

  • M. Castells (1996) The Rise of the Network Society Blackwell Oxford and Malden, MA

    Google Scholar 

  • M. Cimoli (Eds) (2000) Developing Innovation Systems: Mexico in a Global Context Continuum London

    Google Scholar 

  • InstitutionalAuthorNameCouncil of the European Communities, and Commission of the European Communities (1992) Treaty on European Union Office for Official Publications of the European Communities Luxemburg

    Google Scholar 

  • P. Coveney R. Highfield (1990) The Arrow of Time Allen London

    Google Scholar 

  • R. Cowan D. Foray (1997) ArticleTitle‘The Economics of Codification and the Diffusion of Knowledge’ Industrial and Corporate Change 6 595–622

    Google Scholar 

  • P.A. David (1985) ArticleTitle‘Clio and the Economics of Qwerty’ American Economic Review 75 332–337

    Google Scholar 

  • P.A David D. Foray (2002) ArticleTitle‘An Introduction to the Economy of the Knowledge Society’ International Social Science Journal 54 IssueID171 9–23 Occurrence Handle10.1111/1468-2451.00355

    Article  Google Scholar 

  • G. Dei Ottati (2003) Local Governance and Industrial Districts’ Competitive Advantage G. Beccatini M. Bellandi G. dei Ottati F. Sforzi (Eds) From Industrial Districts to Local Development: An Itinerary of Research Edward Elgar Cheltenham UK/Northampton MA 108–130

    Google Scholar 

  • G. Dosi (1982) ArticleTitle‘Technological Paradigms and Technological Trajectories: A Suggested Interpretation of the Determinants and Directions of Technical Change’ Research Policy 11 147–162 Occurrence Handle10.1016/0048-7333(82)90016-6

    Article  Google Scholar 

  • C. Edqvist (Eds) (1997) Systems of Innovation: Technologies, Institutions and Organizations Pinter London

    Google Scholar 

  • H. Etzkowitz L. Leydesdorff (1998) ArticleTitle‘The Endless Transition: A “Triple Helix” of University-Industry-Government Relations’ Minerva 36 203–208 Occurrence Handle10.1023/A:1004348123030

    Article  Google Scholar 

  • H. Etzkowitz L. Leydesdorff (2000) ArticleTitle‘The Dynamics of Innovation: From National Systems and ‘Mode 2’ to a Triple Helix of university–industry–government relations’ Research Policy 29 IssueID2 109–123

    Google Scholar 

  • H. Etzkowitz L. Leydesdorff (Eds) (1997) Universities in the Global Knowledge Economy: A Triple Helix of university–industry–government relations Pinter London

    Google Scholar 

  • H. Etzkowitz A. Webster C. Gebhardt B.R.C. Terra (2000) ArticleTitle‘The Future of the University and the University of the Future: Evolution of Ivory Tower to Entrepreneurial Paradigm’ Research Policy 29 IssueID2 313–330

    Google Scholar 

  • D. Foray B.-A. Lundvall (1996) ‘The Knowledge-Based Economy: From the Economics of Knowledge to the Learning Economy,’ OECD Documents: Employment and Growth in the Knowledge-Based Economy OECD Paris 11–32

    Google Scholar 

  • C. Freeman (1987) Technology Policy and Economic Performance: Lessons from Japan Pinter London

    Google Scholar 

  • C. Freeman (1988) Japan, a New System of Innovation G. Dosi C. Freeman R.R. Nelson G. Silverberg L. Soete (Eds) Technical Change and Economic Theory Pinter London 31–54

    Google Scholar 

  • C. Freeman C. Perez (1988) Structural Crises of Adjustment, Business Cycles and Investment Behaviour G. Dosi C. Freeman R.N.G. Silverberg L. Soete (Eds) Technical Change and Economic Theory Pinter London 38–66

    Google Scholar 

  • C. Freeman L. Soete (1997) The Economics of Industrial Innovation Printer London

    Google Scholar 

  • K. Frenken (2005) Innovation, Evolution and Complexity Theory Edward Elgar Cheltenham, UK/Northampton, MA

    Google Scholar 

  • K. Frenken L. Leydesdorff (2000) ArticleTitle‘Scaling Trajectories in Civil Aircraft (1913–1970)’ Research Policy 29 IssueID3 331–348 Occurrence Handle10.1016/S0048-7333(99)00037-2

    Article  Google Scholar 

  • J.K. Galbraith (1967) The New Industrial State Penguin Harmondsworth

    Google Scholar 

  • M. Gibbons C. Limoges H. Nowotny S. Schwartzman P. Scott M. Trow (1994) The New Production of Knowledge: The Dynamics of Science and Research in Contemporary Societies Sage London

    Google Scholar 

  • A. Giddens (1981) Agency, Institution, and Time-Space Analysis K.D. Knorr-Cetina A.V. Cicourel (Eds) Advances in Social Theory and Methodology. Toward an Integration of Micro- and Macro-Sociologies Routledge and Kegan Paul London 161–174

    Google Scholar 

  • B. Godin (2006) ArticleTitle‘The Knowledge-Based Economy: Conceptual Framework or Buzzword,’ Journal of Technology Transfer 31 IssueID1 17–31

    Google Scholar 

  • P.A. Hall D.W. Soskice (Eds) (2001) Varieties of Capitalism: The Institutional Foundations of Comparative Advantage Oxford University Press Oxford, etc

    Google Scholar 

  • T.P. Hughes (1987) The Evolution of Large Technological Systems W. Bijker T.P. Hughes T. Pinch (Eds) The Social Construction of Technological Systems MIT Press Cambridge 51–82

    Google Scholar 

  • J. Irvine B.R. Martin (1984) Foresight in Science: Picking the Winners Frances Pinter London

    Google Scholar 

  • C. Kampmann C. Haxholdt E. Mosekilde J.D. Sterman (1994) Entrainment in a Disaggregated Long-Wave Model L. Leydesdorff P. Besselaar ParticleVan den (Eds) Evolutionary Economics and Chaos Theory: New Directions in Technology Studies Pinter London/New York 109–124

    Google Scholar 

  • R. Kemp J. Schot R. Hoogma (1998) ArticleTitle‘Regime Shifts to Sustainability through Processes of Niche Formation: The Approach of Strategic Niche Management’ Technology Analysis and Strategic Management 10 IssueID2 175–195

    Google Scholar 

  • G. Krauss H.-G. Wolff (2002) ArticleTitle‘Technological Strengths in Mature Sectors–an Impediment of an Asset of Regional Economic Restructuring? The Case of Multimedia and Biotechnology in Baden-Württemberg’ Journal of Technology Transfer 27 IssueID1 39–50 Occurrence Handle10.1023/A:1013144519815

    Article  Google Scholar 

  • Laafia, I., 1999, ‘Regional Employment in High Technology’, Eurostat, at http://europa.eu.int/comm/eurostat

  • K.J. Lancaster (1979) Variety, Equity and Efficiency Columbia University Press New York

    Google Scholar 

  • B. Latour (1987) Science in Action Open University Press Milton Keynes

    Google Scholar 

  • P.F. Lazarsfeld N.W. Henry (1968) Latent Structure Analysis Houghton Mifflin Boston

    Google Scholar 

  • L. Leydesdorff (1995) The Challenge of Scientometrics: The Development, Measurement, and Self-Organization of Scientific Communications DSWO Press, Leiden University, Leiden

    Google Scholar 

  • L. Leydesdorff (2000) ArticleTitle‘Is the European Union Becoming a Single Publication System?’ Scientometrics 47 IssueID2 265–280 Occurrence Handle10.1023/A:1005639026643

    Article  Google Scholar 

  • Leydesdorff, L., 2001, ‘Indicators of Innovation in a Knowledge-Based Economy,’ Cybermetrics, 5 (Issue 1), Paper 2, athttp://www.cindoc.csic.es/cybermetrics/articles/v5i1p2.html

  • L. Leydesdorff (2003a) ArticleTitle‘The Construction and Globalization of the Knowledge Base in Inter-Human Communication Systems’ Canadian Journal of Communication 28 IssueID3 267–289

    Google Scholar 

  • L. Leydesdorff (2003b) ArticleTitle‘The Mutual Information of University–Industry–Government Relations: An Indicator of the Triple Helix Dynamics’ Scientometrics 58 IssueID2 445–467

    Google Scholar 

  • L. Leydesdorff H. Etzkowitz (1998) ArticleTitle‘The Triple Helix as a Model for Innovation Studies’ Science and Public Policy 25 IssueID3 195–203

    Google Scholar 

  • L. Leydesdorff M. Meyer (2003) ArticleTitle‘The Triple Helix of University-Industry-Government Relations: Introduction to the Tropical Issue’ Scientometrics 58 IssueID2 191–203

    Google Scholar 

  • L. Leydesdorff P. Besselaar ParticleVan den (1998) ArticleTitle‘Technological Development and Factor Substitution in a Non-Linear Model’ Journal of Social and Evolutionary Systems 21 173–192 Occurrence Handle10.1016/S1061-7361(00)80004-1

    Article  Google Scholar 

  • S.J. Liebowitz S.E. Margolis (1999) Winners, Losers & Microsoft: Competition and Antitrust in High Technology The Independent Institute Oakland, CA

    Google Scholar 

  • F. List (1841) The National Systems of Political Economy Longman, 1904 London

    Google Scholar 

  • Luhmann, N., 1984. Soziale Systeme. Grundrißeiner allgemeinen Theorie. Frankfurt a. M.: Suhrkamp

  • N. Luhmann (1996) ArticleTitle‘On the Scientific Context of the Concept of Communication’ Social Science Information 35 IssueID2 257–267

    Google Scholar 

  • B.-Å. Lundvall (1988) Innovation as an Interactive Process: From User–Producer Interaction to the National System of Innovation G. Dosi C. Freeman R. Nelson G. Silverberg L. Soete (Eds) Technical Change and Economic Theory Pinter London 349–369

    Google Scholar 

  • B.-Å. Lundvall (Eds) (1992) National Systems of Innovation Pinter London

    Google Scholar 

  • F. Machlup (1962) The Production and Distribution of Knowledge in the United States Princeton University Press Princeton

    Google Scholar 

  • K. Marx (1848) The Communist Manifesto. Paris. (Translated by Samuel Moore in 1888) Penguin, 1967 Harmondsworth

    Google Scholar 

  • H.R. Maturana (1978) Biology of Language: The Epistemology of Reality G.A. Miller E. Lenneberg (Eds) Psychology and Biology of Language and Thought. Essays in Honor of Erick Lennenberg Academic Press New York 27–63

    Google Scholar 

  • Montesquieu, C., de Sécondat, Baron de, 1748, De l’esprit des lois, Paris.

  • M. Moso M. Olazaran (2002) ArticleTitle‘Regional Technology Policy and the Emergence of an R&D System in the Basque Country’ Journal of Technology Transfer 27 IssueID1 61–75 Occurrence Handle10.1023/A:1013148620724

    Article  Google Scholar 

  • D.C. Mowery N. Rosenberg (1979) ArticleTitle‘The Influence of Market Demand Upon Innovation: A Critical Review of Some Empirical Studies’ Research Policy 8 102–153 Occurrence Handle10.1016/0048-7333(79)90019-2

    Article  Google Scholar 

  • InstitutionalAuthorNameNational Science Board (1987) Science & Engineering Indicators – 1987 National Science Foundation Washington, DC

    Google Scholar 

  • R.R. Nelson (Eds) (1982) Government and Technical Progress: A Cross-Industry Analysis Pergamon New York

    Google Scholar 

  • R.R. Nelson (Eds) (1993) National Innovation Systems: A Comparative Analysis Oxford University Press New York

    Google Scholar 

  • R.R. Nelson S.G. Winter (1975) ArticleTitle‘Growth Theory from an Evolutionary Perspective: The Differential Productivity Growth Puzzle’ American Economic Review 65 338–344

    Google Scholar 

  • R.R. Nelson S.G. Winter (1977) ArticleTitle‘In Search of Useful Theory of Innovation’ Research Policy 6 35–76 Occurrence Handle10.1016/0048-7333(77)90029-4

    Article  Google Scholar 

  • O. Neurath (1933) ArticleTitle‘Protokollsätze’ Erkenntnis 3 204–214

    Google Scholar 

  • H. Nowotny P. Scott M. Gibbons (2001) Re-Thinking Science: Knowledge and the Public in an Age of Uncertainty Polity Cambridge

    Google Scholar 

  • InstitutionalAuthorNameOECD (1980) Technical Change and Economic Policy OECD Paris

    Google Scholar 

  • InstitutionalAuthorNameOECD (1996) OECD Economic Outlook, No. 60 OECD Paris

    Google Scholar 

  • InstitutionalAuthorNameOECD/Eurostat (1997) Proposed Guidelines for Collecting and Interpreting Innovation Data, “Oslo Manual” OECD Paris

    Google Scholar 

  • K. Pavitt (1984) ArticleTitle‘Sectoral Patterns of Technical Change: Towards a Theory and a Taxonomy’ Research Policy 13 343–373 Occurrence Handle10.1016/0048-7333(84)90018-0

    Article  Google Scholar 

  • M.E. Porter (1990) The Competitive Advantage of Nations Macmillan London

    Google Scholar 

  • M. Riba-Vilanova L. Leydesdorff (2001) ArticleTitle‘Why Catalonia Cannot be Considered as Regional Innovation System’ Scientometrics 50 IssueID2 215–240

    Google Scholar 

  • R. Rosen (1985) Anticipatory Systems: Philosophical, Mathematical and Methodological Foundations Pergamon Press Oxford

    Google Scholar 

  • N. Rosenberg (1982) ‘Learning by Using,’ Inside the Black Box: Technology and Economics Cambridge University Press Cambridge etc. 120–140

    Google Scholar 

  • R. Rothwell W. Zegveld (1981) Industrial Innovation and Public Policy Pinter London

    Google Scholar 

  • Rousseau, R., 1999, ‘Daily Time Series of Common Single Word Searches in Altavista and Northernlight,’ Cybermetrics 2/3, Paper 2 at http://www.cindoc.csic.es/cybermetrics/articles/v2i1p2.html

  • D. Sahal (1985) ArticleTitle‘Technological Guideposts and Innovation Avenues’ Research Policy 14 61–82 Occurrence Handle10.1016/0048-7333(85)90015-0

    Article  Google Scholar 

  • P.P. Saviotti (1996) Technological Evolution, Variety and the Economy Edward Elgar Cheltenham & Brookfield

    Google Scholar 

  • F. Sforzi (2003) The ‘Tuscan Model’ and Recent Trends G. Beccatini M. Bellandi G. dei Ottati F. Sforzi (Eds) From Industrial Districts to Local Developments: An Itinerary of Research Edward Elgar Cheltenham, UK/Northampton, MA 29–61

    Google Scholar 

  • T. Shinn (2002) ArticleTitle‘The Triple Helix and New Production of Knowledge: Prepackaged Thinking on Science and Technology’ Social Studies of Science 32 IssueID4 599–614 Occurrence Handle10.1177/030631202128967271

    Article  Google Scholar 

  • E.B. Skolnikoff (1993) The Elusive Transformation: Science, Technology and the Evolution of International Politics Princeton University Press Princeton

    Google Scholar 

  • R.M. Solow (1957) ArticleTitle‘Technical Progress and the Aggregate Production Function’ Review of Economics and Statistics 39 312–320

    Google Scholar 

  • M. Teubal (1979) On User Needs and Need Determination. Aspects of a Theory of Technological Innovation M.J. Baker (Eds) Industrial Innovation. Technology, Policy and Diffusion Macmillan Press London 266–289

    Google Scholar 

  • Theil H., 1972. Statiscal Decomposition Analysis, Amsterdam/London: North-Holland

  • A.M. Turing (1952) Philosophical transactions of the Royal Society, Series B 237 5–72 Occurrence Handle10.1098/rstb.1952.0012

    Article  Google Scholar 

  • J. Urry (2003) Global Complexity Polity Cambridge, UK

    Google Scholar 

  • J. Utterback F.F. Suarez (1993) ArticleTitle‘Innovations, Competition, and Industry Structure’ Research Policy 22 1–22

    Google Scholar 

  • P. Van den Besselaar (1998) Technology and Democracy, the Limits to Steering R.H. Chatfield S. Kuhn M. Muller (Eds) Broadening Participation—5th PDC CPSR Seattle 1–10

    Google Scholar 

  • R. Viale S. Campodall’Orto (2002) ArticleTitle‘An Evolutionary Triple Helix to Strengthen Academy–Industry Relations: Suggestions from European Regions’ Science and Public Policy 29 IssueID3 154–168

    Google Scholar 

  • R.D. Whitley (1999) Divergent Capitalisms: The Social Structuring and Change of Business Systems Oxford University Press New York

    Google Scholar 

  • R.D. Whitley (2001) National Innovation Systems N.J. Smelser P.B. Baltes (Eds) International Encyclopedia of the Social and Behavioral Sciences Elsevier Oxford, UK 10,303–10,309

    Google Scholar 

  • O. Williamson (1985) The Economic Institutions of Capitalism Free Press New York

    Google Scholar 

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Leydesdorff, L. “While a Storm is Raging on the Open Sea”: Regional Development in a Knowledge-based Economy. J Technol Transfer 31, 189–203 (2006). https://doi.org/10.1007/s10961-005-5030-6

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