Universality in Bacterial Colonies
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The emergent spatial patterns generated by growing bacterial colonies have been the focus of intense study in physics during the last twenty years. Both experimental and theoretical investigations have made possible a clear qualitative picture of the different structures that such colonies can exhibit, depending on the medium on which they are growing. However, there are relatively few quantitative descriptions of these patterns. In this paper, we use a mechanistically detailed simulation framework to measure the scaling exponents associated with the advancing fronts of bacterial colonies on hard agar substrata, aiming to discern the universality class to which the system belongs. We show that the universal behavior exhibited by the colonies can be much richer than previously reported, and we propose the possibility of up to four different sub-phases within the medium-to-high nutrient concentration regime. We hypothesize that the quenched disorder that characterizes one of these sub-phases is an emergent property of the growth and division of bacteria competing for limited space and nutrients.
KeywordsComputational biology Interfaces in random media (Theory) Self-affine roughness (Theory)
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- 15.Shimada, H., Ikeda, T., Wakita, J.-I., Itoh, H., Kurosu, S., Hiramatsu, F., Nakatsuchi, M., Yamazaki, Y., Matsuyama, T., Matsushita, M.: Dependence of local cell density on concentric ring colony formation by bacterial species Bacillus Subtilis. J. Phys. Soc. Jpn. 189, 1082–1089 (2004) ADSCrossRefGoogle Scholar
- 28.Bonachela, J.A., Nadell, C.D., Xavier, J.B., Levin, S.A.: in preparation (2011) Google Scholar
- 30.Xavier, J.B., Picioreanu, C., Van Loosdrecht, M.C.M.: Assesment of three-dimensional biofilm models through direct comparison with confocal microscopy imaging. Water Sci. Technol. 49, 177–185 (2004) Google Scholar
- 32.Eden, M.: In: Neyman, J. (ed.) Proc. 4th Berkeley Symp. Mathematical Statistics and Probability, p. 223. University of California Press, Berkeley (1961) Google Scholar
- 39.Monod, J.: Technique de culture continue. Theory et applications. Ann. Inst. Pasteur 79, 390–410 (1950) Google Scholar