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Solubility and Solution Thermodynamic Properties of 4-(4-Hydroxyphenyl)-2-butanone (Raspberry Ketone) in Different Pure Solvents

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Abstract

The solubility of 4-(4-hydroxyphenyl)-2-butanone (raspberry ketone) in six pure solvents was experimentally determined at temperatures ranging from 283.15 to 313.15 K under the pressure 0.10 MPa by employing a gravimetrical method. The experimental results indicate that the solubility of raspberry ketone in all studied solvents is temperature dependent, a rise in temperature brings about an increase in solubility. The experimental solubility data of raspberry ketone in six pure solvents (acetone, ethanol, ethyl acetate, n-propyl alcohol, n-butyl alcohol, and distilled water) was correlated by using several commonly used thermodynamic models, including the Apelblat, van’t Hoff and λh equations. The results of the error analysis indicate that the van’t Hoff equation was able to give more accurate and reliable predictions of solubility with root-mean-square deviation less than 0.56%. Furthermore, the changes of dissolution enthalpies (Δdiss H°), dissolution entropies (Δdiss S°) and dissolution Gibbs energies (Δdiss G°) of raspberry ketone in the solvents studied were estimated by the van’t Hoff equation. The positive value of Δdiss H°, Δdiss S°, and Δdiss G° indicated that these dissolution processes of raspberry ketone in the solvents studied were all endothermic and enthalpy-driven.

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Acknowledgements

The financial supports of the Tianjin Research Program of Application Foundation and Advanced Technology (No. 14JCZDJC40900), The Training Program for Changjiang Scholars and Innovative Research Team in University ([2013]373) and the Innovative Research Team of Tianjin Municipal Education Commission (TD12-5004) are gratefully acknowledged.

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Authors and Affiliations

  1. Tianjin Key Laboratory of Marine Resources and Chemistry, College of Material Science and Chemical Engineering, Tianjin University of Science & Technology, Tianjin, 300457, People’s Republic of China

    Min Shu, Liang Zhu, Liyu Wang, Yanfei Wang, Libin Yang & Zuoliang Sha

  2. Tianjin Academy of Environmental Science, Tianjin, 300191, People’s Republic of China

    Min Yuan & Meng Zeng

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  1. Min Shu
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  2. Liang Zhu
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  3. Min Yuan
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  4. Liyu Wang
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  5. Yanfei Wang
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  6. Libin Yang
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  7. Zuoliang Sha
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  8. Meng Zeng
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Correspondence to Liang Zhu or Min Yuan.

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Shu, M., Zhu, L., Yuan, M. et al. Solubility and Solution Thermodynamic Properties of 4-(4-Hydroxyphenyl)-2-butanone (Raspberry Ketone) in Different Pure Solvents. J Solution Chem 46, 1995–2013 (2017). https://doi.org/10.1007/s10953-017-0681-0

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  • DOI: https://doi.org/10.1007/s10953-017-0681-0

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