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Potentiometric Studies of Ternary Complexes Involving Palladium(II) with Fluoxetine Drug and Some Bio-ligands

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Abstract

The complex formation equilibria of [Pd(FLX)(H2O)2]2+, where FLX = the drug fluoxetine, with the bio-ligands (L), glycine, serine, cysteine, histidine, glycylglycine and glycylvaline, were studied and their formation constants were determined. Stoichiometries and stability constants of the complexes were determined at 25 °C and at constant 0.10 mol·dm−3 NaNO3 ionic strength. The concentration distribution of the complexes in solution was evaluated. Palladium(II) complexes were synthesized and characterized by the 1H NMR and electronic spectral studies. The structures consist of monomeric units in which the Pd(II) atoms exhibit square planar geometry.

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Acknowledgements

The authors would like to thank the Deanship of Scientific Research at Princess Nourah bint Abdul Rahman University for funding this research (37-S-175).

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Authors and Affiliations

  1. Department of Chemistry, College of Science, Princess Nourah bint Abdul Rahman University, Riyadh, Saudi Arabia

    R. A. Ammar & S. D. Al-Qahtani

  2. Deanship of Scientific Research, Princess Nourah bint Abdul Rahman University, Riyadh, Saudi Arabia

    R. A. Ammar & S. D. Al-Qahtani

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  1. R. A. Ammar
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  2. S. D. Al-Qahtani
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Correspondence to R. A. Ammar.

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Ammar, R.A., Al-Qahtani, S.D. Potentiometric Studies of Ternary Complexes Involving Palladium(II) with Fluoxetine Drug and Some Bio-ligands. J Solution Chem 46, 957–965 (2017). https://doi.org/10.1007/s10953-017-0611-1

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