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The Partial Molar Isothermal Compressions of the Nucleosides Adenosine, Cytidine, and Uridine in Aqueous Solution at T = (288.15 and 313.15) K

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Abstract

Sound speeds have been measured for aqueous solutions of the nucleosides adenosine, cytidine, and uridine at T = (288.15 and 313.15) K and at ambient pressure. The partial molar isentropic compressions at infinite dilution, \( K_{S,2}^{\text{o}} \), were derived from the speed of sound data. The partial molar heat capacities at infinite dilution, \( C_{p,2}^{\text{o}} \), for the three nucleosides at T = (288.15 and 313.15) K were also determined. These \( K_{S,2}^{\text{o}} \) and \( C_{p,2}^{\text{o}} \) results, along with partial molar isobaric expansions at infinite dilution, \( E_{2}^{\text{o}} = \, (\partial V_{2}^{\text{o}} /\partial T)_{p} \), that were derived using data from the literature, were used to evaluate the partial molar isothermal compressions at infinite dilution, \( K_{T,2}^{\text{o}} \{ K_{T,2}^{\text{o}} = - \, (\partial V_{2}^{\text{o}} /\partial p)_{T} \} \), for the nucleosides. The \( K_{T,2}^{\text{o}} \) results were rationalized in terms of nucleoside hydration and its temperature dependence.

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Acknowledgements

We thank Inger Johanne Fjellanger for her assistance with some of the speed of sound measurements and Einar Høgseth for his technical expertise in the maintenance of the speed of sound equipment.

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Authors and Affiliations

  1. Institute of Fundamental Sciences-Chemistry, Massey University, Private Bag 11 222, Palmerston North, New Zealand

    Gavin R. Hedwig

  2. Department of Chemistry, University of Bergen, N-5020, Bergen, Norway

    Harald Høiland

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Correspondence to Gavin R. Hedwig.

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Hedwig, G.R., Høiland, H. The Partial Molar Isothermal Compressions of the Nucleosides Adenosine, Cytidine, and Uridine in Aqueous Solution at T = (288.15 and 313.15) K. J Solution Chem 46, 849–861 (2017). https://doi.org/10.1007/s10953-017-0606-y

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