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Ternary Complexes Formed Among Pd(II) Ions, Nucleobases, Nucleosides, Nucleotides and Some Biologically Important Compounds

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Abstract

Potentiometric measurements have been performed at (25.0 ± 0.1) °C and ionic strength I = 0.1 mol·L−1 KNO3 for the interaction of guanine, thymine, uracil, aminouracil, guanosine, inosine, cytidine, guanosine 5′-monophosphate, adenosine 5′-diphosphate, adenosine 5′-triphosphate and palladium Pd(II) with the biologically important secondary ligands glycine, leucine, N,N-bis(2-hydroxyethyl) glycine, N-[tris(hydroxymethyl)methyl] glycine, d-2-t-butylglycine and Boc-N-methyl-l-leucine. The formation of various 1:1:1 ternary complexes and 1:1:2 quaternary complex species as well as the polynuclear species was inferred from the potentiometric pH-titration curves. The experimental conditions were selected such that self-association of the nucleobases, nucleosides or nucleotides and their complexes due to stacking interaction is negligibly small; that is, the normal monomeric protonated ternary complexes were studied. Formation of the ternary complexes of some systems was confirmed using cyclic voltammetry, differential pulse voltammetry and conductance measurements in solution.

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Acknowledgments

The authors thanks Prof. Dr. B. Lippert, professor of inorganic chemistry at Dortmund University, Germany, for assistance and helpful discussions during a DFG Grant in Dortmund.

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Authors and Affiliations

  1. Chemistry Department, Faculty of Science, Suez Canal University, Ismailia, 41522, Egypt

    Hassan A. Azab & Zeinab. M. Anwar

  2. Chemistry Department, Faculty of Science, Suez University, Suez, 43518, Egypt

    Rasha M. Kamel

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  1. Hassan A. Azab
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  2. Zeinab. M. Anwar
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  3. Rasha M. Kamel
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Correspondence to Rasha M. Kamel.

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Azab, H.A., Anwar, Z.M. & Kamel, R.M. Ternary Complexes Formed Among Pd(II) Ions, Nucleobases, Nucleosides, Nucleotides and Some Biologically Important Compounds. J Solution Chem 45, 1095–1114 (2016). https://doi.org/10.1007/s10953-016-0495-5

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