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Density, Viscosity and Refraction Index of Aqueous Solutions of 7-Hydroxycoumarin and Ethanol or 1-Propanol at Temperatures from 293.15 to 313.15 K

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Abstract

7-Hydroxycoumarin exhibits antioxidative, lipoxygenase inhibitive and anti-tumourigenic effects. Density and viscosity measurements have been carried out for the solutions of 7-hydroxycoumarin in mixture solvents of water and ethanol or 1-propanol at T = (293.15, 298.15, 303.15, 308.15 and 313.15) K. The measured data have been used to evaluate apparent molar volumes (V ϕ ), limiting apparent molar volumes (\( V_{\phi }^{0} \)), viscosity B-coefficients of the Jones–Dole equation and variation of B with temperature (dB/dT). The values of \( V_{\phi }^{0} \) and B-coefficients are positive and pass through their corresponding maxima at about 18 mol·kg−1 ethanol molality and 20 mol·kg−1 1-propanol molality, respectively. Besides, the values of \( V_{\phi }^{0} \) and B-coefficients decrease with increasing temperature. Molar refractive indices (R D) of the ternary solutions at the temperature of 298.15 K have also been determined from measured refractive indices (n D). There is an obvious increase of R D with increasing molality of the solvent. These parameters have been interpreted in terms of solute–solvent interactions and structure making/breaking ability of components in the aqueous solution. The temperature and concentration dependences of the weak interactions in the solution systems have also been discussed.

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Acknowledgments

The authors are thankful to the National Natural Science Foundation of China for support (Grant No. 21103079). This work was also supported by Innovation Program for Graduate Education of Shandong Province (SDYC 10044/LCUYZ 10008), Tai-Shan Scholar Research Fund of Shandong Province, and Natural Science Foundation of Zhejiang Province (LQ12B03001).

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Authors and Affiliations

  1. School of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng, 252059, China

    Aiju Chen, Min Liu, Yan Zheng & Dezhi Sun

  2. School of Pharmaceutical, Liaocheng University, Liaocheng, 252059, China

    Bingquan Wang

  3. Zhejiang Medical College, Hangzhou, 310053, China

    Xu Wang

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  1. Aiju Chen
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  2. Min Liu
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  3. Yan Zheng
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Correspondence to Min Liu.

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Chen, A., Liu, M., Zheng, Y. et al. Density, Viscosity and Refraction Index of Aqueous Solutions of 7-Hydroxycoumarin and Ethanol or 1-Propanol at Temperatures from 293.15 to 313.15 K. J Solution Chem 42, 2213–2228 (2013). https://doi.org/10.1007/s10953-013-0100-0

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