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Interaction Between the Low Molecular Mass Components of Blood Serum and the Vanadium(III)–2,2′-Bipyridine System

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Abstract

The complex species formed between vanadium(III)–2,2′-bipyridine (Bipy) and the small blood serum bioligands lactic (HLac), oxalic (H2Ox), citric (H3Cit) and phosphoric (H3PO4) acids were studied in aqueous solution by means of electromotive forces measurements emf(H) at 25 °C and 3.0 mol⋅dm−3 KCl as the ionic medium. The data were analyzed using the least-squares computational program LETAGROP, taking into account the hydrolytic products of vanadium(III) and the binary complexes formed. Formation of the complexes [V(Bipy)(Lac)]2+, [V(Bipy)(Lac)2]+, [V(OH)2(Bipy)(Lac)] and [V2O(Bipy)2(Lac)2]− were observed in the vanadium(III)–Bipy–HLac system. Also, the species [V(Bipy)(HOx)]2+, [V(Bipy)(Ox)]+, [V(OH)(Bipy)(Ox)], [V(OH)2(Bipy)(Ox)]− and [V(OH)3(Bipy)(Ox)]2− were found in the vanadium(III)–Bipy–H2Ox system, the complexes [V(Bipy)(HCit)]+, [V(Bipy)(Cit)], [V(OH)(Bipy)(Cit)]− and [V(OH)2(Bipy)(Cit)]2− were found in the vanadium(III)–Bipy–H3Cit system, and the species [V(Bipy)(H2PO4)]2+ and [V(Bipy)(HPO4)]+ were detected in the vanadium(III)–Bipy–H3PO4 system. The stability constants of these complexes were determined.

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Acknowledgements

We wish to acknowledge the Decanato de Investigación y Desarrollo (DID) from Simón Bolívar University for financial support. We also acknowledge Professors Antonio Barriola, Antonio Zapata, and Simón López from the Simón Bolívar University for their help during this work.

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Authors and Affiliations

  1. Centro de Equilibrios en Solución, Escuela de Química, Facultad de Ciencias, Universidad Central de Venezuela, Caracas, Venezuela

    Freddy Rojas, José Daniel Martínez, Mary Lorena Araujo & Felipe Brito

  2. Departamento de Química, Universidad Simón Bolívar (USB), Apartado 89000, Caracas, 1080 A, Venezuela

    Giuseppe Lubes, Mildred Rodriguez & Vito Lubes

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  1. Freddy Rojas
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  2. José Daniel Martínez
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  3. Mary Lorena Araujo
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  4. Felipe Brito
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  5. Giuseppe Lubes
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  6. Mildred Rodriguez
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  7. Vito Lubes
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Correspondence to Vito Lubes.

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Rojas, F., Martínez, J.D., Araujo, M.L. et al. Interaction Between the Low Molecular Mass Components of Blood Serum and the Vanadium(III)–2,2′-Bipyridine System. J Solution Chem 41, 804–812 (2012). https://doi.org/10.1007/s10953-012-9837-0

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