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The Partial Molar Heat Capacities and Expansions of Inosine, 2′-Deoxyinosine and 2′-Deoxyguanosine in Aqueous Solution at 298.15 K

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Abstract

Solution densities over the temperature range 288.15 to 313.15 K have been measured for aqueous solutions of the nucleosides inosine, 2′-deoxyinosine, and 2′-deoxyguanosine, from which the partial molar volumes of the solutes at infinite dilution, V o2 , were obtained. The partial molar expansions for the nucleosides at infinite dilution and 298.15 K, E o2 {E o2 =(∂ V o2 /∂ T) p }, were derived from the V o2 results. The V o2 values at 298.15 K for the two sugars D-ribose and 2-deoxyribose also have been determined. The partial molar heat capacities at infinite dilution for all the solutes, C o p,2 , have been determined at 298.15 K. These V o2 ,E o2 , and C o p,2 results are critically compared with all of the results available from the literature, and the use of group additivity to evaluate these solution thermodynamic properties for the sparingly soluble nucleoside guanosine is explored.

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  1. Institute of Fundamental Sciences—Chemistry, Massey University, Private Bag 11 222, Palmerston North, New Zealand

    Gavin R. Hedwig

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Hedwig, G.R. The Partial Molar Heat Capacities and Expansions of Inosine, 2′-Deoxyinosine and 2′-Deoxyguanosine in Aqueous Solution at 298.15 K. J Solution Chem 38, 1315–1331 (2009). https://doi.org/10.1007/s10953-009-9450-z

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  • DOI: https://doi.org/10.1007/s10953-009-9450-z

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