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A green approach to the development of novel antibacterial cinnamon oil loaded-PVA/egg white foams via Pickering emulsions

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Abstract

Cinnamon essential oil (CEO) has a low water solubility as a bioactive antibacterial agent with a good fragrance. Pickering emulsion template approach was presented for producing the wound dressing to enhance CEO loading in water-based polymer foams. In this scope, β- cyclodextrin/cinnamon oil (β-CD/CEO) inclusion complexes have been utilized as an emulsion stabilizer, whereas CEO and Polyvinyl alcohol/egg white (PVA/EW) polymer blends have been used as an internal and outer phase, respectively. The amounts of the β-CD/CEO inclusion complexes were introduced into the PVA/EW foams at four different ratios (1.5, 3, 4.5, and 6) and their microstructural, optic, physical, swelling, hydrolytic degradation, and hydrophilicity properties were studied. SEM micrographs showed all PVA/EW/CEO foams open and close cell morphologies, while the stereo-microscope showed foams containing in the ratio of β-CD/CEO 1: 6 have a porous surface without shrinkage on its surface. The existence of β-CD/CEO inclusion complexes and physical interaction between polymer matrixes and the inclusion complexes confirmed by FT-IR spectroscopy. Moreover, the obtained foams have ideal hydrophilicity compatible with the skin with contact angle values ranging from 62.5° ± 3.1° to 70° ± 3.5°. Hydrolytic degradation of the foams decreased as the amount of CEO increased, and the values of more than 80% was seen in the foams at the end of 28 days. Even if CEO volatilized during the process, CEO-loaded PVA/EW foams indicated good antibacterial activity against Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa bacteria with 10–20 mm zone inhibition values. Consequently, the produced PVA/EW/CEO polymer foams with Pickering emulsion approach demonstrated promising results for wound dressings.

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Acknowledgements

The author gratefully acknowledge Dr. Uğur Parın for his kind help in the antibacterial measurements of the foams and Aydın Adnan Menderes University of Faculty of Veterinary Science, Microbiological Department. The author thanks to acknowledge Enver BAYDIR for his kind help in the contact angle measurements and BTU Chemical Engineering Department. SEM micrographs has been carried out in Bursa Technical University Central Research Laboratory, for a fee.

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This study did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

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  1. Faculty of Engineering and Natural Sciences, Department of Polymer Materials Engineering, Bursa Technical University, 16310, Bursa, Turkey

    Fatma Nur Parın

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Parın, F.N. A green approach to the development of novel antibacterial cinnamon oil loaded-PVA/egg white foams via Pickering emulsions. J Porous Mater 30, 1233–1243 (2023). https://doi.org/10.1007/s10934-022-01417-9

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