Synthesis and size control of uniform, spherically shaped hexagonal mesoporous silica

  • Benjawan Moongraksathum
  • Yu-Wen Chen


Spherical hexagonal mesoporous silica (HMS) was prepared at ambient temperature using dodecylamine (DDA) as the template and tetraethyl orthosilicate (TEOS) as the silica source. The properties of the HMS particles were characterised by X-ray powder diffraction, scanning electron microscopy and N2 sorption measurements, and the effects of DDA concentration, stirring speed and rate of TEOS addition were evaluated. The HMS samples exhibited substantial framework-confined and textural mesoporosity. The particle and pore sizes of the spherical HMS decreased with decreasing DDA concentration. With increasing stirring speed, the HMS particle size decreased slightly, and the size distribution narrowed. Increasing the rate of TEOS addition resulted in a decrease in HMS particle size. The findings indicate that DDA concentration, stirring speed and rate of TEOS addition are all important in controlling particle size and shape during HMS synthesis.


Hexagonal mesoporous silica Mesoporous material Silicate Spheroids 



This research was supported by the Ministry of Science and Technology, Taiwan.


  1. 1.
    J.S. Beck, J.C. Vartuli, W.J. Roth, M.E. Leonowicz, C.T. Kresge, K.D. Schmitt et al., J. Am. Chem. Soc. 114, 10834 (1992)CrossRefGoogle Scholar
  2. 2.
    C.T. Kresge, M.E. Leonowicz, W.J. Roth, J.C. Vartuli, J.S. Beck, Nature 359, 710 (1992)CrossRefGoogle Scholar
  3. 3.
    C. Zamani, X. Illa, S. Abdollahzadeh-Ghom, J.R. Morante, A.R. Rodríguez, Nanoscale Res. Lett. 4, 1303 (2009)CrossRefGoogle Scholar
  4. 4.
    W.-S. Chiang, E. Fratini, P. Baglioni, J.-H. Chen, Y. Liu, Langmuir 32, 8849 (2016)CrossRefGoogle Scholar
  5. 5.
    O. Verho, F. Gao, E.V. Johnston, W. Wan, A. Nagendiran, H. Zheng, J. Bäckvall, X. Zou, APL Mater. 2, 113316 (2014)CrossRefGoogle Scholar
  6. 6.
    A. Watermann, Nanomaterials 7, 189 (2017)CrossRefGoogle Scholar
  7. 7.
    R.R. Castillo, A. Baeza, M. Vallet-Regí, Biomater. Sci. 5, 353 (2017)CrossRefGoogle Scholar
  8. 8.
    L.F. Giraldo, B.L. López, L. Pérez, S. Urrego, L. Sierra, M. Mesa, Macromol. Symp. 258, 129 (2007)CrossRefGoogle Scholar
  9. 9.
    C. Mou, H. Lin, Pure Appl. Chem. 72, 137 (2000)CrossRefGoogle Scholar
  10. 10.
    P.T. Tanev, T.J. Pinnavaia, Science 267, 865 (1995)CrossRefGoogle Scholar
  11. 11.
    T.R. Pauly, Y. Liu, T.J. Pinnavaia, S.J.L. Billinge, T.P. Rieker, J. Am. Chem. Soc. 121, 8835 (1999)CrossRefGoogle Scholar
  12. 12.
    W. Zhang, T.R. Pauly, T.J. Pinnavaia, Chem. Mater. 9, 2491 (1997)CrossRefGoogle Scholar
  13. 13.
    T.R. Pauly, T.J. Pinnavaia, Chem. Mater. 13, 987 (2001)CrossRefGoogle Scholar
  14. 14.
    W. Shan, B. Wang, Y. Zhang, Y. Tang, Chem. Commun. 1877 (2005)Google Scholar
  15. 15.
    J. Hu, W. Shan, W. Zhang, Y. Zhang, Y. Tang, Microporous Mesoporous Mater. 129, 210 (2010)CrossRefGoogle Scholar
  16. 16.
    S. Schacht, Q. Huo, I.G. Voigt-Martin, G.D. Stucky, F. Schuth, Science 273, 768 (1996)CrossRefGoogle Scholar
  17. 17.
    X. Zhang, Z. Qu, J. Jia, Y. Wang, Powder Technol. 230, 212 (2012)CrossRefGoogle Scholar
  18. 18.
    M. Schoen, O. Paris, G. Günther, D. Müter, J. Prass, P. Fratzl, Phys. Chem. Chem. Phys. 12, 11267 (2010)CrossRefGoogle Scholar
  19. 19.
    Q.S. Huo, J.L. Feng, F. Schuth, G.D. Stucky, Chem. Mater. 9, 14 (1997)CrossRefGoogle Scholar
  20. 20.
    A. Mehmood, H. Ghafar, S. Yaqoob, U.F. Gohar, B. Ahmad, J. Dev. Drugs 6, 174 (2017)CrossRefGoogle Scholar
  21. 21.
    P.T. Tanev, T.J. Pinnavaia, Chem. Mater. 8, 2068 (1996)CrossRefGoogle Scholar
  22. 22.
    N.V. Jadhav, P.R. Vavia, AAPS PharmSciTech 18, 2764 (2017)CrossRefGoogle Scholar
  23. 23.
    S.-H. Wu, C.-Y. Mou, H.-P. Lin, Chem. Soc. Rev. 42, 3862 (2013)CrossRefGoogle Scholar
  24. 24.
    A. Liberman, N. Mendez, W.C. Trogler, A.C. Kummel, Surf. Sci. Rep. 69, 132 (2014)CrossRefGoogle Scholar

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Authors and Affiliations

  1. 1.Department of Chemical and Materials EngineeringNational Central UniversityJhong-LiTaiwan
  2. 2.Department of ChemistryTomsk State UniversityTomskRussia

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