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Preparation and characterization of micronized zeolite Na-A: cytotoxic activity of silver exchanged form

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Abstract

Very pure micronized zeolite-A (Z-A) and its Ag-exchanged form (Z-Ag) were prepared from purified Egyptian kaolin (K) using microwave irradiation at low temperature. Microstructures of the synthesized material were characterized using FTIR, XRD, SEM and EDS elemental analysis. The weight percent of silver exchanged onto the zeolite structure was determined by atomic absorption spectra. The vitro cytotoxic results of Z-Ag against lung carcinoma cell line (A549), human hepatocellular carcinoma cell line (HePG2), colon cell line carcinoma (HCT116), and human Caucasian breast adenocarcinoma (MCF7) were reported. The results were promising and revealed that the Ag-substituted micronized zeolite-A can be used as novel antitumor drug.

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References

  1. D.W. Breck, J. Chem. Educ. 41, 678–689 (1964)

    Article  CAS  Google Scholar 

  2. G.A. Armenta, G.H. Ramirez, E.F. Loyola, A.U. Castaneda, R.S. Gonzalez, C.T. Munoz, A.J. Lopez, E.R. Castellon, J. Phys. Chem. B 105, 1313–1319 (2001)

    Article  Google Scholar 

  3. K. Pavelić, M. Hadzija, in Medical Application of Zeolites, ed. by S.M. Auerbach, K.A. Carrado, P.K. Dutta (Marcel Dekker, Inc., New York, Basel, 2003)

  4. Z.H. Li, S.J. Roy, Y.Q. Zou, R.S. Bowman, Environ. Sci. Technol. 32, 2628–2632 (1998)

    Article  CAS  Google Scholar 

  5. H. Liu, H.M. Kao, C.P. Grey, in Proceedings of the 12th Internaional Conference Zeolites, ed. by M.J.M. Tracy, B.K. Marcus, Me. Bisher, J.R. Higgins (Material Research Society, P.A. Warrendale, 1999), pp. 2317–2340

  6. A. Seidel, A. Gutsze, B. Boddenberg, in Proceedings of the 12th International Conference Zeolites, ed. by M.J.M. Tracy, B.K. Marcus, Me. Bisher, J.R. Higgins, (Material Research Society, P. A. Warrendale, 1999), pp. 2589–2618

  7. G.R. Fuentes, A.R. Denis, M.B. Alvarez, A.I. Colarte, Microporous Mesoporous Mater. 94, 200–207 (2006)

    Article  Google Scholar 

  8. G. Rodriguez-Fuentes, M.A. Barrios, A. Iraizoz, I. Perdomo, B. Cedre, Zeolites 19, 441–448 (1997)

    Article  CAS  Google Scholar 

  9. B. Concepciόn-Rosabal, J. Balmaseda-Era, G. Rodriguez-Fuentes, Microporous Mesoporous Mater. 38, 161–166 (2000)

    Article  Google Scholar 

  10. R. Simon-Carballo, A. Fleitas, J. Alvarez, G. Rodriguez-Fuentes, Hypocholesterolemic Action of Cholestine in Cholesterol Fed Animals, Zeolite’97: Occurrence, Properties, and Utilization of Natural Zeolites (Program and Abstracts) (De Frede, Naples, 1997), pp. 106–108

    Google Scholar 

  11. B. Concepcion-Rosabal, G. Rodriguez-Fuentes, R. Simon-Carballo, Zeolites 19, 47–50 (1997)

    Article  CAS  Google Scholar 

  12. A. Ueki, M. Yamaguchi, H. Ueki, Y. Watanabe, G. Ohsawa, K. Kinugawa, Y. Kawakami, F. Hydoh, Immunology 82, 332–335 (1994)

    CAS  Google Scholar 

  13. T. Aikoh, A. Tomokuni, T. Matsukii, F. Hydoh, H. Ueki, T. Otsuki, A. Ueki, Int. J. Oncol. 12, 1355–1359 (1998)

    CAS  Google Scholar 

  14. K. Pavelic, M. Hadzija, L.J. Bedrica, J. Pavelic, I. Dikic, M. Katic, M. Kralj, M.H. Bosnar, S. Kapitanovic, M. Poljak-Blazi, S. Krizanac, R. Stojkovic, M. Jurin, B. Subotic, M. Colic, J. Mol. Med. 78, 708–720 (2001)

    Article  CAS  Google Scholar 

  15. K. Pavelic, M. Katic, V. Sverko, T. Marotti, B. Bosnjak, T. Balog, R. Stojkovic, M. Radacic, M. Colic, M. Poljak-Blazi, J. Cancer Res. Clin. Oncol. 128, 37–44 (2002)

    Article  CAS  Google Scholar 

  16. T. Tsuda, Y. Morimoto, H. Yamato, H. Nakamura, H. Hori, N. Nagata, M. Kido, T. Higashi, I. Tanaka, Environ. Health Prosp. 105, 1173–1178 (1997)

    Article  CAS  Google Scholar 

  17. Y. Lim, S.H. Kim, K.A. Kim, M.W. Oh, K.H. Lee, Environ. Health Prosp. 105, 1325–1327 (1997)

    Article  CAS  Google Scholar 

  18. P. Simeonova, W. Torium, C. Kommineni, M. Erkan, A.E. Muson, W.N. Rom, M.I. Luster, J. Immunol. 59, 3921–3928 (1997)

    Google Scholar 

  19. M. Poljak-Blazi, M. Katic, M. Kralj, N. Zarkovic, T. Marotti, B. Bosnjak, V. Sverko, T. Balog, K. Pavelic, Stud. Surf. Sci. Catal. 135, 5309–5316 (2001)

    CAS  Google Scholar 

  20. N. Zarkovic, K. Zarkovic, M. Kralj, S. Borovic, S. Sabolovic, M. Poljak-Blazi, A. Cipak, K. Pavelic, Anticancer Res. 23(2B), 1589–1595 (2003)

    CAS  Google Scholar 

  21. J.C. Jansen, A. Arafat, A.K. Barakat, H. van Bekkum, in Synthesis of Microporous Materials, vol. 1, ed. by M.L. Occelli, H.E. Robson (Van Nostrand Reinhold, New York, 1992), p. 507

  22. S. Komarneni, M. Tsuji, J. Am. Ceram. Soc. 72, 1668–1674 (1989)

    Article  CAS  Google Scholar 

  23. K.J. Rao, B. Vaidhyanathan, M. Ganguli, P.A. Ramakrishnan, Chem. Mater. 11, 882–895 (1999)

    Article  CAS  Google Scholar 

  24. R. Szostak, Handbook of Molecular Sieves (van Nostrand Reinhold, New York, 1992), pp. 258–440

    Google Scholar 

  25. J.C.M. Muller, G. Hakvoort, J.C. Jansen, J. Thermal. Anal. 53, 258–261 (1998)

    Google Scholar 

  26. V.H. Bekkum, E.M. Flanigen, P.A. Jacobs, J.C Jansen, in Introduction to Zeolite Science and Practice, 2nd rev. edn. (Elsevier, Amsterdam, 1991), pp. 13–33

  27. S. Demiric, Z. Ustaoglu, G.A. Yilmazer, F. Sahin, N. Bac, Appl. Biochem. Biotechnol. 172, 1652–1662 (2014)

    Article  Google Scholar 

  28. K. Shameli, M.B. Ahmad, W.M.Z.W. Yunus et al., Int. J. Nanomed. 5, 875–887 (2010)

    Article  CAS  Google Scholar 

  29. M.B. Ahmad, K. Shameli, W.M.Z.W. Yunus et al., Res. J. Biol. Sci. 4, 1032–1036 (2009)

    Google Scholar 

  30. N. Duran, P.D. Marcarto, G.I.H. De Souza, O.L. Alves, E. Esposito, J. Biomed. Nanotechnol. 3, 203–208 (2007)

    Article  CAS  Google Scholar 

  31. H.F. Youssef, D.M. Ibrahim, S. Komarneni, Microporous Mesoporous Mater. 115, 527–534 (2008)

    Article  CAS  Google Scholar 

  32. Y. Abe, M. Ueshige, M. Takeuchi, M. Ishii, Y. Akagawa, Int. J. Prosthodont. 16, 141–144 (2003)

    Google Scholar 

  33. M.M. Cowan, K.Z. Abshire, S.L. Houk, S.M. Evans, J. Ind. Microbiol. Biotechnol. 30, 102–106 (2003)

    Article  CAS  Google Scholar 

  34. M. Hotta, H. Nakajima, K. Yamamoto, M. Aono, J. Oral Rehabil. 25, 485–489 (1998)

    Article  CAS  Google Scholar 

  35. G.N. Kirov, G. Terziiski, Comparative study of clinoptilolite and Zeolite-A as antimicrobial agents, in Natural Zeolite-Sofia’95, ed. by G. Kirov, L. Filizova, O. Petrov (Pensoft, Sofia, 1997), pp. 133–141

    Google Scholar 

  36. T. Ozawa, Fuel Energy Abstr. 38, 29–32 (1997)

    Google Scholar 

  37. M. Rivera-Garza, M.T. Olguı´n, I. Garcı´a-Sosa, D. Alca´ntara, G. Rodrı´guez-Fuentes, Microporous Mesoporous Mater. 39, 431–444 (2000)

    Article  CAS  Google Scholar 

  38. N. Zarkovic, K. Zarkovic, M. Kralj, S. Borovic, S. Sabolovic, M.P. Blazi, A. Cipak, K. Pavelic, Anticancer Res. 23, 1589–1596 (2003)

    CAS  Google Scholar 

  39. G. Narin, Ç.B. Albayrak, S. Ülkü, App. Clay Sci. 50, 560–568 (2010)

    Article  CAS  Google Scholar 

  40. J. Wang, Z. Wang, S. Guo, J. Zhang, Y. Song, X. Dong, X. Wang, J. Yu, Microporous Mesoporous Mater. 146, 216–222 (2011)

    Article  CAS  Google Scholar 

  41. A. Lam, A. Rivera, Microporous Mesoporous Mater. 91, 181–186 (2006)

    Article  CAS  Google Scholar 

  42. GhS Hassan, ShM El-Messery, F.A.M. Al-Omary, S.T. Al-Rashood, M.I. El-Hallouty, W. Fayed, KhM Mohamed, B.S. El-Menshawi, H.I. El-Subbagh, Eur. J. Med. Chem. 66, 135–145 (2013)

    Article  CAS  Google Scholar 

  43. M.R. Grever, S.A. Schepartz, B.A. Chabner, Semin. Oncol. 19, 622–638 (1992)

    CAS  Google Scholar 

  44. A. Monks, D. Scudiero, P. Skehan, R. Shoemaker, K. Paull, D. Vistica, C. Hose, J. Langley, P. Cronise, A. Vaigro-Wolff, M. Gray-Goodrich, H. Campbell, J. Mayo, M. Boyd, J. Natl Cancer Inst. 83, 757–766 (1991)

    Article  CAS  Google Scholar 

  45. M.R. Boyd, K.D. Paull, Drug Rev. Res. 34, 91–109 (1995)

    Article  CAS  Google Scholar 

  46. B.S. El-Menshawi, W. Fayad, K. Mahmoud, S.M. El-Hallouty, M. El-Manawaty, M.H. Olofsson, S. Linder, Indian J. Exp. Biol. 48, 258–264 (2010)

    Google Scholar 

  47. S. Chandrasekhar, P. Raghavan, G. Sebastian, A.D. Damodaran, Appl. Clay Sci. 12, 221–231 (1997)

    Article  CAS  Google Scholar 

  48. D. Bougeard, K.S. Smirnov, E. Geidel, J. Phys. Chem. B 104, 9210–9217 (2000)

    Article  CAS  Google Scholar 

  49. M.J. Sánchez, P. Gamero, D. Cortés, Mater. Lett. 74, 250–253 (2012)

    Article  Google Scholar 

  50. T. Mosmann, J. Immunol. Methods 65, 55–63 (1983)

    Article  CAS  Google Scholar 

  51. M.I. Thabrew, R.D. Hughes, I.G. McFarlane, J. Pharm. Pharmacol. 49, 1132–1135 (1997)

    Article  CAS  Google Scholar 

  52. H.J. Percival, J.F. Duncan, P.K. Foster, J. Am. Ceram. Soc. 57, 57–61 (1974)

    Article  CAS  Google Scholar 

  53. M. Alkan, C. Hopa, Z. Yilmaz, H. Guler, Microporous Mesoporous Mater. 86, 176–184 (2005)

    Article  CAS  Google Scholar 

  54. D. Akolekar, A. Chaffee, R.F. Howe, Zeolite 19, 359–365 (1997)

    Article  CAS  Google Scholar 

  55. A. Demortier, C. Duhayon, N. Gobeltz, J. Plelieur, Int. J. Inorg. Mater. 1, 129–134 (1999)

    Article  CAS  Google Scholar 

  56. R.M. Barrer, Hydrothermal Chemistry of Zeolites (Academic Press, New York, 1982)

    Google Scholar 

  57. S. Markovica, V. Dondura, R. Dimitrijevicb, J. Molec. Str. 654, 223–234 (2003)

    Article  Google Scholar 

  58. E.M. Flanigen, H. Khatami, H.A. Szymanski, Molecular Sieve Zeolites I, ACS Advanced in Chemistry Series, (Washington, D.C., 1971), pp. 101, 201

  59. H.J. Lee, Y.M. Kim, O.S. Kweon, I.J. Kim, J. Eur. Ceram. Soc. 27, 561–564 (2006)

    Article  Google Scholar 

  60. S. Sang, Z. Liu, P. Tian, Z. Liu, L. Qu, Y. Zhang, Mater. Lett. 60, 131–133 (2006)

    Article  Google Scholar 

  61. F. Shi, L. Wang, J. Liu, Mater. Lett. 60, 3718–3722 (2006)

    Article  CAS  Google Scholar 

  62. K. Shameli, M.B. Ahmad, W.M.Z.W. Yunus et al., Int. J. Nanomed. 5, 743–751 (2010)

    Article  CAS  Google Scholar 

  63. Z. Hagiwara, Sh. Hoshiuo, H. Ishino, S. Nohara, K. Tagawa, K. Yamanaka, U.S. Patent 4,911,898, Mar. 27 1990

  64. S. Gurunathan, K.J. Lee, K. Kalishwaralal, S. Sheikpranbabu, R. Vaidyanathan, S.H. Eom, Biomaterials 30, 6341–6350 (2009)

    Article  CAS  Google Scholar 

  65. D. Martins, L. Frungillo, P.S. Anazzetti Melo, N. Durán, Int. J. Nanomed. 5, 77–85 (2010)

    Article  CAS  Google Scholar 

  66. YuP Blagoi, V.L. Galkin, G.O. Gladchenko et al., Metallokompleksy Nukleinovykh Kislot v Rastvorakh [Metal Complexes of Nucleic Acids in Solutions] (Naukova Dumka, Kiev, 1991)

    Google Scholar 

  67. S. Gurunathan, J. Raman, S. Abd Malek, P.A. John, S. Vikineswary, Int. J. Nanomed. 8, 4399–4413 (2013)

    Google Scholar 

  68. M.I. Sriram, S.B.M. Kanth, K. Kalishwaralal, S. Gurunathan, Int. J. Nanomed. 5, 753–762 (2010)

    CAS  Google Scholar 

  69. P.V. Asha Rani, G. Low Kah Mun, M.P. Hande, S. Valiyaveettil, ACS Nano. 3, 279–290 (2009)

    Article  CAS  Google Scholar 

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Acknowledgments

The authors thank National Research Centre, the microwave laboratory, and Faculty of Science, Suez University for supporting this work.

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Authors and Affiliations

  1. Refractories, Ceramics and Building Materials Department, National Research Centre (NRC), Dokki, Cairo, 12622, Egypt

    H. F. Youssef & H. H. Abo-almaged

  2. Department of Chemistry, Faculty of Science, Suez University, Suez, 43533, Egypt

    W. H. Hegazy

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  1. H. F. Youssef
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Correspondence to W. H. Hegazy.

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Youssef, H.F., Hegazy, W.H. & Abo-almaged, H.H. Preparation and characterization of micronized zeolite Na-A: cytotoxic activity of silver exchanged form. J Porous Mater 22, 1033–1041 (2015). https://doi.org/10.1007/s10934-015-9977-x

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