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Fabrication of bioceramic scaffolds with pre-designed internal architecture by gel casting and indirect stereolithography techniques

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Abstract

A new technique of combining the gel casting and indirect rapid prototyping methods was utilized to fabricate macroporous β-tricalcium phosphate (β-TCP) scaffolds, which provided an excellent control over the internal architecture of scaffolds and enhanced their mechanical properties. A stereolithography apparatus was used to produce resin molds for ceramic gel casting. These molds were filled with a water based thermosetting ceramic slurry which solidifies inside the mold. After burning the resin mold and sintering, the β-TCP scaffolds with designed pore architecture were obtained. The pore morphology, size, and distribution of the resulting scaffolds were characterized using a scanning electron microscope. X-ray diffraction was used to determine the crystal structure and chemical composition of scaffolds. The mechanical measurements showed that the average compressive strength was 16.1 ± 0.8 MPa.

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Acknowledgement

The authors would like to thank the National Natural Science Foundation of China (Grant No. 50235020) for their support to this work.

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Authors and Affiliations

  1. The Institute of Life Quality and Mechanical Engineering, School of Mechanical Engineering, Shanghai Jiaotong University, Shanghai, 200240, China

    Xiang Li & Chengtao Wang

  2. State Key Lab for Manufacturing Systems Engineering, Xi’an Jiaotong University, Xi’an, 710049, China

    Dichen Li & Bingheng Lu

Authors
  1. Xiang Li
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  2. Dichen Li
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  3. Bingheng Lu
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  4. Chengtao Wang
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Correspondence to Xiang Li.

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Li, X., Li, D., Lu, B. et al. Fabrication of bioceramic scaffolds with pre-designed internal architecture by gel casting and indirect stereolithography techniques. J Porous Mater 15, 667–671 (2008). https://doi.org/10.1007/s10934-007-9148-9

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  • DOI: https://doi.org/10.1007/s10934-007-9148-9

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