Journal of Medical Systems

, Volume 31, Issue 5, pp 357–364 | Cite as

Comparison of the Levels of Accuracy of an Artificial Neural Network Model and a Logistic Regression Model for the Diagnosis of Acute Appendicitis

  • Shinya Sakai
  • Kuriko Kobayashi
  • Shin-ichi Toyabe
  • Nozomu Mandai
  • Tatsuo Kanda
  • Kohei Akazawa


An accurate diagnosis of acute appendicitis in the early stage is often difficult, and decision support tools to improve such a diagnosis might be required. This study compared the levels of accuracy of artificial neural network models and logistic regression models for the diagnosis of acute appendicitis. Data from 169 patients presenting with acute abdomen were used for the analyses. Nine variables were used for the evaluation of the accuracy of the two models. The constructed models were validated by the “.632+ bootstrap method”. The levels of accuracy of the two models for diagnosis were compared by error rate and areas under receiver operating characteristic curves. The artificial neural network models provided more accurate results than did the logistic regression models for both indices, especially when categorical variables or normalized variables were used. The most accurate diagnosis was obtained by the artificial neural network model using normalized variables.


Acute appendicitis Artificial neural network Logistic regression Bootstrap 



We thank Ms. Akane Inaizumi, Ms. Atsuko Sugiyama and Mr. Toshikazu Abe for valuable assistance in the acquisition of the data and references. We also thank Dr. Ralph Grams for his kind suggestions.


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Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • Shinya Sakai
    • 1
  • Kuriko Kobayashi
    • 1
  • Shin-ichi Toyabe
    • 2
  • Nozomu Mandai
    • 1
  • Tatsuo Kanda
    • 3
  • Kohei Akazawa
    • 2
  1. 1.Division of Information Science and BiostatisticsNiigata University Graduate School of Medical and Dental SciencesNiigataJapan
  2. 2.Department of Medical InformaticsNiigata University Medical and Dental HospitalNiigataJapan
  3. 3.Division of Digestive and General SurgeryNiigata University Graduate School of Medical and Dental SciencesNiigataJapan

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