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Therapeutic Targeting of Signal Transduction Pathways and Proteins in Breast Cancer

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References

  1. Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57–70.

    Article  PubMed  CAS  Google Scholar 

  2. Condeelis J, Pollard JW. Macrophages: obligate partners for tumor cell migration, invasion, and metastasis. Cell 2006;124:263–6.

    Article  PubMed  CAS  Google Scholar 

  3. Slamon DJ, Leyland-Jones B, Shak S, Fuchs H, Paton V, Bajamonde A, et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 2001;344:783–92

    Article  PubMed  CAS  Google Scholar 

  4. Piccart-Gebhart MJ, Procter M, Leyland-Jones B, Goldhirsch A, Untch M, Smith I, et al. Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. N Engl J Med 2005;353:1659–72.

    Article  PubMed  CAS  Google Scholar 

  5. Wullschleger S, Loewith R, Hall MN. TOR signaling in growth and metabolism. Cell 2006;124:471–84.

    Article  PubMed  CAS  Google Scholar 

  6. Karin M, Cao Y, Greten FR, Li ZW. NF-kappaB in cancer: from innocent bystander to major culprit. Nat Rev Cancer 2002;2:301–10.

    Article  PubMed  CAS  Google Scholar 

  7. Greten FR, Eckmann L, Greten TF, Park JM, Li ZW, Egan LJ, et al. IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell 2004;118:285–96.

    Article  PubMed  CAS  Google Scholar 

  8. Wiener Z, Ontsouka EC, Jakob S, Torgler R, Falus A, Mueller C, et al. Synergistic induction of the Fas (CD95) ligand promoter by Max and NFkappaB in human non-small lung cancer cells. Exp Cell Res 2004;299:227–35.

    Article  PubMed  CAS  Google Scholar 

  9. Robbins J, Blondel BJ, Gallahan D, Callahan R. Mouse mammary tumor gene int-3: a member of the notch gene family transforms mammary epithelial cells. J Virol 1992;66:2594–99.

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland

    Nancy E. Hynes

  2. Cancer Biology Laboratory, Research School of Biosciences, University of Kent, Canterbury, UK

    William Gullick

Authors
  1. Nancy E. Hynes
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  2. William Gullick
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Correspondence to Nancy E. Hynes.

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Hynes, N.E., Gullick, W. Therapeutic Targeting of Signal Transduction Pathways and Proteins in Breast Cancer. J Mammary Gland Biol Neoplasia 11, 1–2 (2006). https://doi.org/10.1007/s10911-006-9007-3

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  • DOI: https://doi.org/10.1007/s10911-006-9007-3

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