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Two New Metal–Organic Frameworks: Photoluminescent Property and Prevention on the Hypotension After Anesthesia by Activating the α Receptor on the Peripheral Blood Vessels

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Abstract

Two novel metal–organic compounds have been prepared via altering metal ions under the hydrothermal conditions, i.e. [Zn(HL)(4,4′-bipy)(H2O)2]n (1) and [Cd(HL)(4,4′-bipy)]n (2) (4,4′-bipy = 4,4′-bipyridine and H3L = 5-(4-carboxyphenoxy)-isophthalic acid). Moreover, the luminescent performances and stabilities of the two compounds were also investigated. For the prevention and treatment evaluation of compounds 1 and 2 in this present research, serious of biological experiments were performed in this study. Firstly, the non-invasive blood pressure monitoring was used for blood pressure determination. In addition to this, the real time RT-PCR assay was conducted in this study for the assessment of the α receptor expression on the vascular endothelial cells.

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Authors and Affiliations

  1. Department of Anesthesiology, Jiangle General Hospital of Fujian Province, Sanming, Fujian, China

    Li-Xiong Nie, Quan-Ming Qiu, Shun-Nian Qiu, Min Lan & Gao-Feng Wang

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  1. Li-Xiong Nie
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Correspondence to Quan-Ming Qiu.

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10904_2021_1906_MOESM1_ESM.doc

CCDC Nos. 2026174-2026175 contain the supplementary crystallographic data for this paper. These data can be obtained free of charge at www.ccdc.cam.ac.uk/conts/retrieving.html [or from the Cambridge Crystallographic Data Centre, 12, Union Road, Cambridge CB2 1EZ, UK; fax: (internet.) +44 1223/336 033; E-mail: deposit@ccdc.cam.ac.uk]. (DOC 78 kb)

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Nie, LX., Qiu, QM., Qiu, SN. et al. Two New Metal–Organic Frameworks: Photoluminescent Property and Prevention on the Hypotension After Anesthesia by Activating the α Receptor on the Peripheral Blood Vessels. J Inorg Organomet Polym 31, 2990–2998 (2021). https://doi.org/10.1007/s10904-021-01906-5

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