A Facile Approach to Generate Cross-Linked Poly(cyclotriphosphazene-co-oxyresveratrol) Nanoparticle with Intrinsically Fluorescence
- 86 Downloads
Highly cross-linked and monodisperse polyphosphazene nanoparticles exhibiting strong fluorescence with oxyresvertrol structure was facilely generated via a one-pot prediction polycondensation of hexachlorocyclotriphosphazene and oxyresveratrol. The results reveal that the diameter of the microspheres can be well adjusted (typically in a range from 200 to 400 nm). Attractively, the as-prepared nanoparticle with oxyresveratrol structure possess outstanding disperse ability in both aqueous and organic media. Moreover, it exhibits significantly enhanced fluorescent intensity and outstanding photobleaching stability under ultraviolet–visible irradiation, owing to the highly cross-linked and organic–inorganic hybrid structure. Due to these superior properties and novelty of our synthesized material, it has shown great potential in application as fluorescent labels, carriers and potent biomaterials in drug delivery.
KeywordFacile Oxyresveratrol Nanoparticle Fluorescent Cross-linked Drug delivery
This work was supported by Natural Science Foundation of China (Nos. 21274092, 91441205), and Shanghai Science & Technology Committee (No. 10ZR1416100) and Shanghai Munucipal Planning Commission and Research Fund (No. 2010258).
- 8.N. Vijayasree, K. Haritha, V. Subhash, K.R.S.S. Rao, Res. J. Biotechnol. 4, 61–66 (2009)Google Scholar
- 17.P. Sharma, S. Brown, G. Walter, S. Santra, B. Moudgil, Adv. Coll. Interf. Sci. 471, 123–126 (2006)Google Scholar
- 22.M.J.S. Dewar, E.A.C. Lucken, M.A. Whitehead, J. Chem. Soc. 2423–2429 (1960)Google Scholar
- 29.W. Wei, X.B. Huang, K.Y. Chen, X.Z. Tang, RSC. Adv. 37, 65–71 (2012)Google Scholar