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Synthesis and Characterization of Chitosan-Coated Cobalt Ferrite Nanoparticles and Their Antimicrobial Activity

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Abstract

Chitosan-coated cobalt ferrites were synthesized by wet ferritization method through two different approaches. The nanostructured chitosan-coated cobalt ferrites were characterized by: X-ray diffraction (XRD), scanning electron microscopy (FE-SEM), transmission electron microscopy (TEM/HR-TEM), thermal analysis, infrared spectroscopy (IR) and Mössbauer spectroscopy. X-ray diffraction patterns confirmed the formation of CoFe2O4 cubic spinel structure with an average crystallite size of 1.75 and 5.5 nm, respectively. Mössbauer spectra consist in a central quadrupole pattern. The deconvolution in the hypothesis of Lorentzian line shape evidences the prevailing presence of Fe3+ ions at the nanoparticle surface. The antimicrobial activity of chitosan-coated cobalt ferrites against Gram-positive and Gram-negative bacteria, as well as fungal strains was investigated. Based on the results, chitosan-coated cobalt ferrites are thought to be suitable candidates for the development of novel anti-biofilm agents.

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Acknowledgements

The work benefited from the support of the European Union (ERDF) and Romanian Government under the POS-CCE O 2.2.1 project INFRANANOCHEM - Nr. 19/01.03.2009. The work also benefits from the support of the “Materials Science and Advanced Characterization Methods” Programme of the “Ilie Murgulescu” Institute of Physical Chemistry, financed by the Romanian Academy. One of the authors (L.D.) acknowledges the financial support under Core program PN 10N as well of the European Union and Romanian Government, under POS-CCE project CEUREMAVSU-Nr.01/01.03.2009.

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Authors and Affiliations

  1. “Ilie Murgulescu” Institute of Physical Chemistry, Romanian Academy, Splaiul Independentei 202, 060021, Bucharest, Romania

    Dana Gingasu, Ioana Mindru, Luminita Patron, Gabriela Marinescu & Silviu Preda

  2. Faculty of Applied Chemistry and Materials Science, “Politehnica” University of Bucharest, Polizu Street 1-7, 011061, Bucharest, Romania

    Adelina Ianculescu, Eugeniu Vasile & Ovidiu Oprea

  3. National Institute of Materials Physics (NIMP), Atomistilor Street 405 A, P. O. Box Mg-7, 077125, Bucharest–Magurele, Romania

    Lucian Diamandescu

  4. Microbiology Department, Faculty of Biology, University of Bucharest, Splaiul Independentei 91-95, Bucharest, Romania

    Marcela Popa, Crina Saviuc & Mariana Carmen Chifiriuc

  5. Life, Environmental and Earth Sciences Division, Research Institute of the University of Bucharest, Splaiul Independentei 91-95, Bucharest, Romania

    Marcela Popa, Crina Saviuc & Mariana Carmen Chifiriuc

Authors
  1. Dana Gingasu
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  2. Ioana Mindru
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  8. Lucian Diamandescu
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  10. Marcela Popa
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  11. Crina Saviuc
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  12. Mariana Carmen Chifiriuc
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Correspondence to Ioana Mindru or Lucian Diamandescu.

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Gingasu, D., Mindru, I., Patron, L. et al. Synthesis and Characterization of Chitosan-Coated Cobalt Ferrite Nanoparticles and Their Antimicrobial Activity. J Inorg Organomet Polym 28, 1932–1941 (2018). https://doi.org/10.1007/s10904-018-0870-3

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  • DOI: https://doi.org/10.1007/s10904-018-0870-3

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