Can Spherical Vaterite Be Biomimetic Synthesized by Using Histidine-Grafted-Chitosan as an Organic Matrix?
Extensive application of vaterite in ceramics, biomedical implanting, encapsulation and drug delivery require the effectively controlling the size, morphology and polymorph of the obtained calcium carbonate. For this purpose, vaterite was synthesized by using histidine-grafted-chitosan (NHCS) as an organic matrix in this research. The effects of the initial concentration of NHCS, and the aging time on the morphology and polymorph were investigated. The prepared vaterite was characterized by field-emission scanning electron microscope, Fourier transform infrared spectrometer and X-ray diffraction. The result showed vaterite has presented as an advantage phase over calcite phase in presence of NHCS system, and the 91.6 wt% percentage of vaterite can be achieved when the initial concentration of NHCS is 1.000 mg L−1. Prolonging aging time from 0 to 24 h, the percentage of vaterite would be deduced from 94.4 to 86.2 wt%, in which the flaky-floret and multilayered vaterite transforms to calcite slowly. In contrast, a single crystalline rhombohedral calcite phase can only be obtained without adding NHCS in pure water system. The possible growth mechanism has been proposed by investigating the transition of crystal phase and formation of the vaterite during the growth process. The result indicates that NHCS is an effective template to biomimetic synthesis of vaterite, and provides a novel method for controlling synthesis other biomaterials.
KeywordsVaterite Biomimetic synthesis Histidine-grafted-chitosan Template Initial concentration Aging time
This work is supported by the National Science Foundation of China (21103095, 21206079), Fujian Provincial Natural Science Foundation (2015J01057, 2015J01644, 2017J01590, 2017J01710), Scientific Research Plan of Education Bureau of Fujian Province (JAT160431), Projects of Putian University (2015060, 2016015, 2016065).
- 8.T. Kasuga, A. Obata, H. Maeda, Y. Ota, X.F. Yao, K. Oribe, J. Mater. Sci. 23, 2349–2357 (2012)Google Scholar
- 17.X.D. Chen, M.H. Xin, M.C. Li, Z.X. Chen, Z.Q. Chen, Chin. J. Mater. Res. 30, 31–37 (2016)Google Scholar
- 26.B. Schrader, D. Bougeard (eds.), Infrared and Raman spectroscopy (VCH, Weinheim, New York, 1995)Google Scholar
- 32.I. Polowczyk, A. Bastrzyk, T. Kozlecki, Physicochem. Probl. Miner. Process. 49, 631–639 (2013)Google Scholar
- 38.J.Y. Wang, Biochemistry (China Higher Education Press, Beijing, 2008)Google Scholar