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Home Blood Pressure Monitoring And Nocturia In Adults

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Abstract

Although widely viewed as a urological condition, nocturia has been increasingly recognized to accompany various non-urological conditions such as hypertension and blood pressure (BP) elevation on office determination. Home BP monitoring (HBPM) has been shown superior to office-based readings and provides an opportunity to assess potential relationships between nocturia and novel indices derived from multiple BP recordings including BP load, BP variability, and arterial stiffness, which have prognostic significance. We retrospectively studied 103 home BP logs and nocturia frequencies provided by 61 stable cardiology patients ≥ 21 years without medication change. Nocturnal voids ranged from 0 to 5 voids per night, median: 1.5. Nocturia frequency was significantly correlated with home and office systolic BPs and with BP load, but not with diastolic BPs, BP variability or arterial stiffness. On Poisson regression analysis, the estimated prevalence ratio (PR) for home and office systolic BPs were 1.025 (CI: 1.01, 1.04; p < .001) and 1.01 (CI:1.00, 1.02; p = .019), indicating 2.5% and 1% increases in the risk of nocturia per mmHg increases in BP respectively. In conclusion, higher mean home and office systolic BPs are associated with self-reported nocturia frequency with stronger associations seen for home BP measurement. Nocturia frequency appears unrelated to mean home and office diastolic BPs. Nocturia may be related to BP load, (percentage of elevated BP values), but not to BP variability or arterial stiffness. Future prospective studies using HBPM are needed to confirm these findings and to contribute to the understanding of the elevated BP-nocturia link.

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Authors and Affiliations

  1. Division of Cardiovascular Medicine, SUNY Downstate Health Sciences University, 450 Clarkson Avenue, MSC 1199, 11203-2098, Brooklyn, NY, USA

    Jason M. Lazar, Alexandra Posner, Kamal Akbar, Gulzhan Tologonova, Rasheda Browne, Sarah Goldman & Louis Salciccioli

  2. Department of Urology, SUNY Downstate Health Sciences University, Brooklyn, NY, USA

    Thomas Monaghan & Jeffrey Weiss

  3. Department of Biostatistics and Epidemiology, School of Public Health, SUNY Downstate Health Sciences University, Brooklyn, NY, USA

    Christopher Murray, Elizabeth Helzner & Rose Calixte

  4. Department of Urology, Ghent University Hospital, Ghent, Belgium

    Karel Everaert

  5. Department of Internal Medicine and Pediatrics, Ghent University Hospital, Ghent, Belgium

    Tine DeBacker

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  1. Jason M. Lazar
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Contributions

CRediT Taxonomy: Conceptualization: Jason Lazar; Methodology: Alexandra Posner, Kamal Akbar, Gulzhan Tologonova, Thomas Monaghan, Sarah Goldman, Rasheda Browne, Jason Lazar; Formal Analysis and Investigation: Christopher Murray, Elizabeth Helzner, Rose Calixte.

Writing – Original Draft Preparation: Jason Lazar, Christopher Murray, Louis Salciccioli, Thomas Monaghan; Writing – Review and Editing: Thomas F. Monaghan, Jeffrey P. Weiss, Karel Everaert, Tine DeBacker, Elizabeth Helzner, Rose Calixte, Louis Salciccioli; Funding Acquisition: N/A; Resources: N/A; Supervision: N/A.

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Correspondence to Jason M. Lazar.

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The present analysis employed retrospectively collected data that required institutional board approval but did not require patient consent.

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Jason M. Lazar has no direct or indirect commercial incentive associated with publishing this article and certifies that all conflicts of interest relevant to the subject matter discussed in the manuscript are the following: Dr. Everaert has served as Promoter for the Ghent University Frederik Paulsen Chair and Medtronic OptiLUTS Chair, is a minority shareholder (without salary) in P2solutions, and has received institutional grants and honoraria from Astellas, Ferring, and Medtronic, outside the submitted work. The additional authors have nothing to disclose.

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Lazar, J.M., Posner, A., Akbar, K. et al. Home Blood Pressure Monitoring And Nocturia In Adults. J Community Health 48, 238–244 (2023). https://doi.org/10.1007/s10900-022-01171-8

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