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Exploring the Gap Between Knowledge and Behavior Regarding Thalassemia Among University Students: A Cross-Sectional Study in the United Arab Emirates

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Abstract

Thalassemia is humanity’s most common genetic disorder and represents a serious healthcare challenge in the United Arab Emirates. Increasing awareness is a crucial part of any successful strategy to prevent thalassemia. This research examined knowledge levels and attitudes regarding thalassemia screening, counseling, and monitoring from medical and nonmedical students at Ajman University. This was a cross-sectional, descriptive study conducted among a convenience sample of Ajman university students in the UAE. A questionnaire was distributed which was composed of three main sections. The first section covered participants’ demographic data. The second section covered general knowledge of thalassemia and its screening measures. The third section assessed risk factors, regulations, and preventive measures. The data were analyzed using the statistical package for social sciences (SPSS) version 24. A total of 523 participants completed the whole survey. Generally, there was a good level of awareness of thalassemia and thalassemia screening among participants. Approximately three-quarters of participants (76.5%) agreed that thalassemia screening should be compulsory for the individual and the majority of students and 92.7% recognized the importance of thalassemia screening for both partners. Approximately three-quarters (75.9%) of participants disagreed that fetuses with thalassemia should be aborted. More than half of the participants disagreed that thalassemia carriers and patients should be prevented from marrying each other. Generally, older respondents (final year students), respondents who had dealt with thalassemia patients, and respondents with relatives with thalassemia had more comprehensive knowledge of thalassemia. Campaigns focusing on college and university students should be regarded as an essential element of the thalassemia prevention strategy for contemporary UAE society.

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References

  1. Thalassemia Foundation of Canada. (2009). Guidelines for the clinical care of patients with thalassemia in Canada. Thalassemia.ca. Available from: http://www.thalassemia.ca/resources/

  2. Cao, A., & Galanello, R. (2010). Beta-thalassemia. Genetics in Medicine., 12(2), 61–76. https://doi.org/10.1097/GIM.0b013e3181cd68ed PMID: 20098328.

    Article  CAS  PubMed  Google Scholar 

  3. Danjou, F., Anni, F., & Galanello, R. (2011). Beta-thalassemia: From genotype to phenotype. Haematologica, 96(11), 1573–1575. https://doi.org/10.3324/haematol.2011.055962 PMID: 22058279.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Weatherall, D. (2010). The inherited diseases of hemoglobin are an emerging global health burden. Blood, 115(22), 4331–4336. https://doi.org/10.1182/blood-2010-01-251348 PMID: 20233970.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Kim, S., & Tridane, A. (2017). Thalassemia in the United Arab Emirates: Why it can be prevented but not eradicated. PLoS One, 12(1), e0170485.

    Article  Google Scholar 

  6. Baysal, E. (2005). Molecular heterogeneity of beta-thalassemia in the United Arab Emirates. Community Genetics., 8(1), 35–39. PMID:15767753.

    Article  CAS  Google Scholar 

  7. Baysal, E. (2011). Molecular basis of β−thalassemia in the United Arab Emirates. Hemoglobin., 35(5–6), 581–588. PMID:22074124.

    Article  CAS  Google Scholar 

  8. Denic, S., Aden, B., Nagelkerke, N., & Essa, A. (2013). β−Thalassemia in Abu Dhabi: Consanguinity and tribal stratification are major factors explaining the high prevalence of the disease. Hemoglobin., 37(4), 351–358. PMID:23600619.

    Article  CAS  Google Scholar 

  9. Al-Dabbagh, B., Shawqi, S., Yasin, J., Al Essa, A., Nagelkerke, N., & Denic, S. (2013). Half of the Emirati population aas abnormal red cell parameters: Challenges for standards and screening guidelines. Hemoglobin., 38(1), 56–59. PMID:24205932.

    Article  Google Scholar 

  10. Al-Gazali, L., Alwash, R., & Abdulrazzaq, Y. (2005). United Arab Emirates: Communities and community genetics. Public Health Genomics, 8(3), 186–196.

    Article  CAS  Google Scholar 

  11. Mitchell, J. J., Capua, A., Clow, C., & Scriver, C. R. (1996). Twenty-year outcome analysis of genetic screening programs for Tay-Sachs and beta-thalassemia disease carriers in high schools. American Journal of Human Genetics, 59(4), 793–798.

    CAS  PubMed  PubMed Central  Google Scholar 

  12. Scriver, C. R., Bardanis, M., Cartier, L., Clow, C. L., Lancaster, G. A., & Ostrowsky, J. T. (1984). Betathalassemia disease prevention: Genetic medicine applied. American Journal of Human Genetics, 36(5), 1024–1038.

    CAS  PubMed  PubMed Central  Google Scholar 

  13. Al, K. R., Al Rujaibi, S., & Al, K. M. (2012). Knowledge and attitude of university students towards premarital screening program. Oman Medical Journal, 27, 291–296. https://doi.org/10.5001/omj.2012.72

    Article  Google Scholar 

  14. Al-Farsi, O. A., Al-Farsi, Y. M., Gupta, I., Ouhtit, A., Al-Farsi, K. S., & Al-Adawi, S. (2014). A study on knowledge, attitude, and practice towards premarital carrier screening among adults attending primary healthcare centers in a region in Oman. BMC Public Health, 14, 380. https://doi.org/10.1186/1471-2458-14-380

    Article  PubMed  PubMed Central  Google Scholar 

  15. Abdel-Meguid, N., Zaki, M. S., & Hammad, S. A. (2000). Premarital genetic investigations: Effect of genetic counselling. Eastern Mediterranean Health Journal, 6, 652–660.

    Article  CAS  Google Scholar 

  16. Eshra, D. K., Dorgham, L. S., & el-Sherbini, A. F. (1989). Knowledge and attitudes towards premarital counselling and examination. Journal of Egypt Public Health Association, 64, 1–15.

    CAS  Google Scholar 

  17. Gharaibeh, H., & Mater, F. K. (2009). Young Syrian adults’ knowledge, perception and attitudes to premarital testing. International Nursing Review, 56, 450–455. https://doi.org/10.1111/j.1466-7657.2009.00736.x

    Article  CAS  PubMed  Google Scholar 

  18. Alkhaldi, S. M., Khatatbeh, M. M., Berggren, V. E., & Taha, H. A. (2016). Knowledge and attitudes toward mandatory premarital screening among university students in North Jordan. Hemoglobin, 40, 1–7. https://doi.org/10.3109/03630269.2015.1135159

    Article  CAS  Google Scholar 

  19. Cao, A., & Kan, Y. W. (2013). The Prevention of Thalassemia. Cold Spring Harbor Perspectives in Medicine., 3(2), a011775.

    Article  Google Scholar 

  20. Hossain, M. S., Hasan, M. M., Raheem, E., Islam, M. S., Al Mosabbir, A., Petrou, M., Telfer, P., Siddiqee, M. H. (2020). Lack of knowledge and misperceptions about thalassaemia among college students in Bangladesh: a cross-sectional baseline study. Orphanet Journal of Rare Diseases, 15(1), 1.

  21. Politis, C., Richardson, C., & Yfantopoulos, J. G. (1991). Public knowledge of thalassemia in Greece and current concepts of the social status of the thalassemic patients. Social Science and Medicine, 32(1), 59–64.

    Article  CAS  Google Scholar 

  22. Okyay, R. A., Celenk, O., Nazlican, E., & Akbaba, M. (2016). Haemoglobinopathy awareness among young students in Turkey: outcomes of a City-wide survey. PLoS One., 11(7), e0159816.

    Article  Google Scholar 

  23. Wong, L. P., George, E., & Tan, J. A. (2011). Public perceptions and attitudes toward thalassaemia: Influencing factors in a multi-racial population. BMC Public Health, 11, 193.

    Article  Google Scholar 

  24. Olwi, D. I., Merdad, L. A., & Ramadan, E. K. (2018). Thalassemia: A prevalent disease yet unknown term among college students in Saudi Arabia. Human Frontier Science Program, 9(3), 277–282.

    Google Scholar 

  25. Hajeri, A. A., & Arrayed, S. A. (2012). Public awareness of Beta thalassemia in Bahrain. Bahrain Medical Bulletin., 34(1), 26–29.

    Google Scholar 

  26. Armeli, C., Robbins, S. J., & Eunpu, D. (2005). Comparing knowledge of beta-thalassemia in samples of Italians, Italian-Americans, and non-Italian-Americans. Journal of Genetic Counseling, 14(5), 365–376.

    Article  Google Scholar 

  27. Wilson, J. M. G., & Jungner, G. (1968). Principles and practice of screening for disease. Public Health Paper, 65, 281–393.

    CAS  Google Scholar 

  28. Cousens, N. E., Gaff, C. L., Metcalfe, S. A., & Delatycki, M. B. (2010). Carrier screening for Beta-thalassaemia: A review of international practice. European Journal of Human Genetics, 18, 1077–1083.

    Article  Google Scholar 

  29. Samavat, A., & Modell, B. (2004). Iranian national thalassaemia screening programme. BMJ, 329, 1134–1137.

    Article  Google Scholar 

  30. Hesketh, T. (2003). Getting married in China: Pass the medical first. BMJ, 326, 277–279.

    Article  Google Scholar 

  31. Ginsberg, G., Tulchinsky, T., Filon, D., Goldfarb, A., Abramov, L., & Rachmilevitz, E. A. (1998). Cost-benefit analysis of a national thalassaemia prevention programme in Israel. Journal of Medical Screening., 5, 120–126.

    Article  CAS  Google Scholar 

  32. Ahmadnezhad, E., Sepehrvand, N., Jahani, F. F., Hatami, S., KargarC, Mirmohammadkhani M., et al. (2012). Evaluation and cost analysis of national health policy of thalassaemia screening in west-azerbaijan province of Iran. International Journal of Preventive Medicine, 3, 687–692.

    PubMed  PubMed Central  Google Scholar 

  33. Mudiyanse, R. M. (2015). Safe marriage for thalassemia prevention; the gap between knowledge and practice among medical students. Austin Journal of Pediatrics., 2(2), 1023.

    Google Scholar 

  34. Mudiyanse, R. M. (2006). Thalassemia Treatment and Prevention in Uva Province Sri Lanka: Public opinion survey. Hemoglobin, 30, 275–289.

    Article  CAS  Google Scholar 

  35. Petrou M. (2013). Genetic Counselling. In: Prevention of Thalassaemias and Other Haemoglobin Disorders: Volume 1: Principles edited by J O, 2nd edition edn. Nicosia, Cyprus: Thalassaemia International Federation.

  36. Al Sulaiman, A., Saeedi, M., Al Suliman, A., & Owaidah, T. (2010). Postmarital follow-up survey on high risk patients subjected to premarital screening program in Saudi Arabia. Prenatal Diagnosis, 30(5), 478–481.

    PubMed  Google Scholar 

  37. Angantiniotis, M. A., & Hadjiminas, M. G. (1981). Prevention of thalassaemia in cyprus. The Lancet, 1, 369–371.

    Article  Google Scholar 

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No funding assisted the preparation of this study.

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Authors and Affiliations

  1. College of Pharmacy and Health Science, Ajman University, Ajman, United Arab Emirates

    Ayat Maher Elsadek, Nageeb Hassan & Moyad Shahwan

  2. Center of Medical and Bio-Allied Health Sciences Research, Ajman University, Ajman, United Arab Emirates

    Nageeb Hassan & Moyad Shahwan

  3. Health and Safety Department, Dubai Municipality, P.O. Box 17666, Dubai, United Arab Emirates

    Ammar Abdulrahman Jairoun

Authors
  1. Ayat Maher Elsadek
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  2. Nageeb Hassan
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  3. Moyad Shahwan
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  4. Ammar Abdulrahman Jairoun
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Correspondence to Ammar Abdulrahman Jairoun.

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Elsadek, A.M., Hassan, N., Shahwan, M. et al. Exploring the Gap Between Knowledge and Behavior Regarding Thalassemia Among University Students: A Cross-Sectional Study in the United Arab Emirates. J Community Health 47, 392–399 (2022). https://doi.org/10.1007/s10900-022-01066-8

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