Journal of Gambling Studies

, Volume 21, Issue 1, pp 109–114 | Cite as

Methodological Problems in Research on Treatments for Pathological Gambling

  • Peter E. Nathan

These common methodological problems affect the usefulness of pathological gambling (PG) treatment research: (1) Most PG etiological models derive from substance abuse; (2) Most PGs recover on their own and few seek treatment, so PGs in treatment studies may not be representative; (3) Data on treatment-seeking PG women, older adults, and minority group members, or on group, marital, and psychodynamic approaches to PG, are sparse; (4) Little research has examined the impact of comorbidity on PG treatment response; (5) Design deficiencies burden many PG treatment studies.


external and internal validity methodological problems pathological gambling research treatment 


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  1. Benjamin, J., Lin, L., Patterson, C., Greenberg, B. D., Murphy, D. L., Hamer, D. H. 1996Population and familial association between the D4 dopamine receptor gene and measures of novelty seekingNature Genetics128183Google Scholar
  2. Briggs, J. R., Goodin, B. J., Nelson, T. 1996Pathological gamblers and alcoholics: Do they share the same addictionAddictive Behaviors21515519Google Scholar
  3. Comings, D. E. 1998The molecular genetics of pathological gamblingCNS Spectrums32037Google Scholar
  4. Cook, D. R. 1987Self-identified addictions and emotional disturbances in a sample of college studentsPsychology of Addictive Behaviors15561Google Scholar
  5. Crockford, D. N., el-Guebaly, N. 1998Psychiatric comorbidity in pathological gambling: A critical reviewCanadian Journal of Psychiatry434350Google Scholar
  6. Ebstein, R. P., Novick, O., Umansky, R., Priel, B., Osher, Y., Blaine, D. 1996Dopamine D4 receptor (D4DR) exon III polymorphism associated with the human personality trait of novelty seekingNature Genetics127880Google Scholar
  7. Gomberg, E. S. L. 1999WomenMcCrady, B. S.Epstein, E. E. eds. Addictions: A comprehensive guidebookOxford University PressNew York527541Google Scholar
  8. Grant, J. E., Kim, S. W. 2002Gender differences in pathological gamblers seeking medication treatmentComprehensive Psychiatry435662Google Scholar
  9. Hodgins, D. D. 2001Processes of changing gambling behaviorAddictive Behaviors26121128Google Scholar
  10. Hodgins, D. C., Makarchuk, K., el-Guebaly, N. 2002Why problem gamblers quit gambling: A comparison of methods and samplesAddiction Research and Theory10203218Google Scholar
  11. Khantzian, E. J. 1997The self-medication hypothesis of addictive disorders: Focus on heroin and cocaine dependenceAmerican Journal of Orthopsychiatry661731Google Scholar
  12. Kim, S. W., Grant, J. E., Adson, D. E. 2002A double-blind placebo-controlled study of the efficacy and safety of paroxetine in the treatment of pathological gamblingJournal of Clinical Psychiatry63501507Google Scholar
  13. Ladouceur, R., Sylain, C., Boutin, C. 2001Cognitive treatment of pathological gamblingJournal of Nervous and Mental Disease189774780Google Scholar
  14. Maccallum, F., Blaszczynski, A. 2002Pathological gambling and comorbid substance useAustralian and New Zealand Journal of Psychiatry36411415Google Scholar
  15. Nathan, P. E., Gorman, J. M. 2002A guide to treatments that work2Oxford University PressNew YorkGoogle Scholar
  16. National Research Council1999Pathological gambling: A critical review.National Academy PressWashington, DCGoogle Scholar
  17. Pallanti, S., Quercioli, L., Sood, E. 2002Lithium and valproate treatment of pathological gambling: A randomized single-blind studyJournal of Clinical Psychiatry63559564Google Scholar
  18. Petry, N. M. 2002A comparison of young, middle-aged, and older adult treatment-seeking pathological gamblersGerontologist429299Google Scholar
  19. Shaffer, H. J. 1999Addiction and gambling disorders: On matters of measurement and validityThe Behavioral Measurement Letter626Google Scholar
  20. Shaffer, H. J., Hall, M. N. 2002The natural history of gambling and drinking problems among casino employeesJournal of Social Psychology142405424Google Scholar
  21. Sobell, L. C., Cunningham, J. A., Sobell, M. B. 1996Recovery from alcohol problems with and without treatment: Prevalence in two population surveysAmerican Journal of Public Health86966972Google Scholar
  22. Toneatto, T., Brennan, J. 2002Pathological gambling in treatment-seeking substance abusersAddictive Behaviors27465469Google Scholar
  23. Toneatto, T., Skinner, W., Dragonetti, R. 2002Patterns of substance use in treatment-seeking problem gamblers: Impact on treatment outcomesJournal of Clinical Psychology58853859Google Scholar
  24. Welte, J., Barnes, G., Wieczorek, W. 2001Alcohol and gambling pathology among U.S. adults: Prevalence, demographic patterns and comorbidity.Journal of Studies on Alcohol62706712Google Scholar

Copyright information

© Springer Science+Business Media, Inc. 2005

Authors and Affiliations

  1. 1.Department of PsychologyUniversity of IowaIowa CityU.S.A.

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