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An Introductory Overview on Applications of Pyrazoles as Transition Metal Chemosensors

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Abstract

Utility of pyrazoles and their derivatives in constructing ordered porous materials with physicochemical characteristics such as chemosensors has undoubtedly created much interest in developing newer frameworks. A variety of pyrazole based chemosensors are known for their remarkable photophysical, pH sensitivity, solvatochromic, ion detection, high quantum yields and nonlinear optical behavior. Many of the transition metals have shown beneficial biological effects in biological systems. There is always a need of continuous monitoring to maintain an adequate range of all and specifically for the toxic ones like mercury. Pyrazoline nanoparticle probes have been reported for sensing/detection of Hg2+ions. Pyridinyl pyrazoline and benzimidazolyl pyrazole derived sensors are more selective and sensitive towards Zn2+and Fe3+ ions respectively. Pyrazole derived metal organic frameworks (MOF’s) have been reported for environmental monitoring and biological imaging. Keeping in view of the enormous synthetic and biological importance of pyrazoles, herein, we are presenting an overview on applications of pyrazoles in transition metal chemosensors.

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Abbreviations

SARS-COV-2RNA :

Severe acute respiratory syndrome coronavirus-2 ribose nucleic acid

BTP:

Bis (2-(2’-benzothienyl)-pyridinato-N, C3’) iridium (acetylacetonate))

Pro4:

Tetraproline

PMS:

Precursor molecular sensor

EWC:

Early fire warning component

TD-DFT:

Time-dependent density-functional theory

TEM:

Transmission electron microscope

TMBPz:

Tetramethyl bis(pyrazole)

L:

Bis(pyrazole)-bis(acetate)

H2BPEFB:

1, 4-Bis (1H-pyrazol-4-ylethynyl)—2- fluorobenzene

HeLa:

Henrietta Lacks

EDTA:

Ethylene diamine tetra acetic acid

HRMS-ESI:

High resolution mass spectra-electrospray ionization

OTC:

Oxytetracycline

DFT:

Density functional theory

BIS:

Bis(acrylamide)

DEAP:

2, 2-Diethoxyacetophenone

QDs:

Quantum Dots

CDs:

Carbon Dots

DCDs:

Dual Emission Carbon Dots

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Acknowledgements

We highly acknowledges Guru Jambheshwar University of Science and Technology, Hisar.

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Authors and Affiliations

  1. Department of Chemistry, Guru Jambheshwar University of Science and Technology, Hisar, Haryana, 125001, India

    Mahavir Parshad, Devinder Kumar & Vikas Verma

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  1. Mahavir Parshad
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Dr Mahavir Parshad had the idea for the article and performed the literature search and data analysis, and Dr Devinder Kumar and Dr Vikas Verma drafted and/or critically revised the work.

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Correspondence to Mahavir Parshad.

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Parshad, M., Kumar, D. & Verma, V. An Introductory Overview on Applications of Pyrazoles as Transition Metal Chemosensors. J Fluoresc (2023). https://doi.org/10.1007/s10895-023-03402-0

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