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Highly Selective Turn-on Fluorescence Sensor for Cd2+ Ions by Tripodal Organic Ligand

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Abstract

Organic fluorescence sensor for selectively detecting and quantifying toxic heavy metal ions has received significant interest due to their environmental hazards. Herein, we have designed and synthesized a simple tripodal Schiff base ligand (1) based on hydroxy-naphthaldehyde and tris(2-aminoethyl)amine (TREN) and demonstrated highly selective turn-on fluorescence sensing of Cd2+ ions. The free ligand did not show any fluorescence in DMF. In contrast, Cd2+ (10− 4 M) addition exhibited a strong enhancement of fluorescence at 450 nm. Interestingly, other metal ions including Zn2+, which exhibit similar chemistry, did not show any turn-on fluorescence. The concentration-dependent studies of 1 with Cd2+ showed the detection limit of 6.78 × 10− 8 M. NMR spectra of 1 with Cd2+ and computational studies were performed to understand the mechanism of sense.

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Funding

Financial support from the Science and Engineering Research Board (SERB), Core Research grant (CRG) (CRG/2020/003978) and DST-FIST (SR/FST/CS-1/2018/62), New Delhi, India is acknowledged with gratitude. Dr BJ sincerely thanks DST-SERB (File No.: SB/FT/CS-169/2012) and DST-DPRP division [File no: VI-D&P/562/2016-17/TDT (C)].

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Authors and Affiliations

  1. Medicinal Organic Chemistry Laboratory, Department of Applied Chemistry, Karunya Institute of Technology and Sciences, Coimbatore, 641 114, Tamil Nadu, India

    Pavankumar Muralakar, Sneha Abraham & Bhagavathsingh Jebasingh

  2. School of Chemical and Biotechnology, SASTRA Deemed University, Thanjavur, 613401, Tamil Nadu, India

    Sasikala Ravi, Parthasarathy Gayathri & Savarimuthu Philip Anthony

  3. Department of Applied Chemistry, HPLC MASS FACILITY, Karunya Institute of Technology and Sciences, Coimbatore, 641114, Tamil Nadu, India

    Bhagavathsingh Jebasingh

  4. Department of Chemistry, Madras Christian College (Autonomous), University of Madras), Chennai, 600 059, India

    Cheriyan Ebenezer & Rajadurai Vijay Solomon

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  1. Pavankumar Muralakar
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Contributions

P.M and S. A performed the synthesis and characterization and S.R and P.G carried-out sensing studies and C.E and R.V.S performed theoretical studies and B.J and S.P.A planned the work and wrote the main manuscript.

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Correspondence to Bhagavathsingh Jebasingh or Savarimuthu Philip Anthony.

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Muralakar, P., Ravi, S., Gayathri, P. et al. Highly Selective Turn-on Fluorescence Sensor for Cd2+ Ions by Tripodal Organic Ligand. J Fluoresc 34, 1229–1240 (2024). https://doi.org/10.1007/s10895-023-03348-3

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