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Fluorescent Sensors for Hg2+ and Cu2+ Based on Condensation Products of 4H-1,2,4 Triazole-4-Amine and Carboxylated Benzoic Acids

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Abstract

Mercury (Hg) causes serious health issues in its all forms. Deficiency as well as excess of copper ion (Cu2+) in human body is hazardous. A series of four compounds have been derived from carboxylated benzoic acids (benzoic acid, isophthalic acid, terephthalic acid and phthalic acid) and 4H-1,2,4 triazole-4-amine and characterized. Fluorescence detection of Hg2+ was recorded by the derivates with benzoic acid and isophthalic acid while the derivatives of terephthalic acid and phthalic acid detect Cu2+ by fluorescence “off” mode. Metal ions like Li+, Na+, K+, Zn2+, Al3+, Mg2+, Mn2+, Co2+, Ni2+, Cu2+, Cd2+, Pb2+ and Hg2+ found not to interfere. The stoichiometry of binding is 1:1 for the benzoic acid derivative with Hg2+ while it is 1:2 for the other three derivatives. The binding constants are ca. 10–4.5 between the sensors and Hg2+ or Cu2+ and detection limits are around 10–5.5 M. DFT calculation provided optimized geometries of the sensors and confirmed the stoichiometry of binding with Hg2+/Cu2+.

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Data sharing not applicable to this article as no datasets were generated or analysed during the current study.

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Acknowledgements

The authors thank DST for financial grant vide MRP (EMR/2016/001745) and FIST to the department. IIT-Kanpur is thanked for HRMS spectra.

Funding

Funding received from DST, New Delhi (EMR/2016/001745).

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Authors and Affiliations

  1. Department of Chemistry, Gauhati University, Guwahati, 781014, India

    Satyapriya Deka & Diganta Kumar Das

  2. Department of Chemistry, Cotton University, Guwahati, 781001, India

    Ankur Kanti Guha

Authors
  1. Satyapriya Deka
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  2. Ankur Kanti Guha
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  3. Diganta Kumar Das
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Contributions

SD has done all the experiments works; AKG has done the computational works; DKD has done analysis of the results and written the paper.

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Correspondence to Diganta Kumar Das.

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Deka, S., Guha, A.K. & Das, D.K. Fluorescent Sensors for Hg2+ and Cu2+ Based on Condensation Products of 4H-1,2,4 Triazole-4-Amine and Carboxylated Benzoic Acids. J Fluoresc 31, 1937–1945 (2021). https://doi.org/10.1007/s10895-021-02777-2

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  • DOI: https://doi.org/10.1007/s10895-021-02777-2

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