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EDC-Induced Self-Assembly of BSA-Au NCs

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Abstract

In this paper, the Au nanoplate with bright red fluorescence was synthesized on the basis of bovine serum albumin stabilized Au nanoclusters (BSA-Au NCs). The small molecule N-ethyl-N′-(dimethylaminopropyl) carbodiimide (EDC) was used as the cross-linking agent to activate the carboxyl group on the surface of BSA, and then the condensation with amino acid in BSA induced the self-assembly of BSA-Au NCs. The particle size of Au nanoplate increased with EDC concentration. In addition, when EDC concentration was 0.0050 M, the Au nanoplate changed from smooth to grainy structure. The Au nanoplate remained the unique fluorescence characteristics of BSA-Au NCs. As EDC concentration reached 0.0025 M, the Au nanoplate even exhibited brighter red emission than that of BSA-Au NCs.

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References

  1. Zheng J, Nicovich PR, Dickson RM (2007) Highly fluorescent noble-metal quantum dots. Annu Rev Phys Chem 58:409–431

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Tao Y, Li M, Ren J, Qu X (2015) Metal nanoclusters: novel probes for diagnostic and therapeutic applications. Chem Soc Rev 44(23):8636–8663

    Article  CAS  PubMed  Google Scholar 

  3. Li H, Zhu W, Wan A, Liu L (2017) The mechanism and application of the protein stabilized gold nanocluster sensing system. Analyst 142:567–581

    Article  CAS  PubMed  Google Scholar 

  4. Xie J, Zheng Y, Jackie YY (2009) Protein-directed synthesis of highly fluorescent gold nanoclusters. J Am Chem Soc 131:888–889

    Article  CAS  PubMed  Google Scholar 

  5. Weller H (1993) Kolloidale Halbleiter-Q-Teilchen: Chemie im Übergangsbereich zwischen Festkörper und Molekül. Angew Chem 105:43–55

    Article  CAS  Google Scholar 

  6. Wang L, Wang Y, Dong S, Deng Y, Hao J (2018) Nanocapsules of magnetic Au self-assembly for DNA migration and secondary self-assembly. ACS Appl Mater Interfaces 10(6):5348–5357

    Article  CAS  PubMed  Google Scholar 

  7. Xiang J, Drzal LT (2011) Electron and Phonon Transport in Au Nanoparticle Decorated Graphene Nanoplatelet Nanostructured Paper. ACS Appl Mater Interfaces 3:1325–1332

    Article  CAS  PubMed  Google Scholar 

  8. Ding B, Deng Z, Yan H, Cabrini S, Zuckermann RN, Bokor J (2010) Gold nanoparticle self-similar chain structure organized by DNA origami. J Am Chem Soc 132:3248–3249

    Article  CAS  PubMed  Google Scholar 

  9. Gupta P, Rajput M, Singla N, Kumar V, Lahiri D (2016) Electric field and current assisted alignment of CNT inside polymer matrix and its effects on electrical and mechanical properties. Polymer 89:119–127

    Article  CAS  Google Scholar 

  10. Lee MJ, Lim SH, Ha JM, Choi SM (2016) Green synthesis of high-purity mesoporous gold sponges using self-assembly of gold nanoparticles induced by thiolated poly(ethylene glycol). Langmuir 32:5937–5945

    Article  CAS  PubMed  Google Scholar 

  11. Li M, Johnson S, Guo HT, Dujardin E, Mann S (2011) A generalized mechanism for ligand-induced dipolar assembly of plasmonic gold nanoparticle chain networks. Adv Funct Mater 21:851–859

    Article  CAS  Google Scholar 

  12. Wang J, Sun CS, Liu XF, Xin LL, Fang Y (2014) Self-assembled au nanoparticle arrays on thiol-functionalized resin beads for sensitive detection of paraquat by surface-enhanced Raman scattering. Colloids and Surfaces A: Physicochem Eng Aspects 455:104–110

    Article  CAS  Google Scholar 

  13. Lee JH, Mahmoud MA, Sitterle V, Sitterle J, Meredith JC (2009) Facile preparation of highly-scattering metalnanoparticle-coated polymer microbeads and their surface plasmon resonance. J Am Chem Soc 131:5048–5049

    Article  CAS  PubMed  Google Scholar 

  14. Lee JH, Mahmoud MA, Sitterle VB, Sitterle JJ, Meredith JC (2009) Highly scattering, surface-enhanced Raman scattering-active, metal nanoparticle-coated polymers prepared via combined swelling-heteroaggregation. Chem Mater 21:5654–5663

    Article  CAS  Google Scholar 

  15. Boal AK, Ilhan F, DeRouchey JE, Thurn-Albrecht T, Russell TP, Rotello VM (2000) Self-assembly of nanoparticles into structured spherical and network aggregates. Nature 404:746–748

    Article  CAS  PubMed  Google Scholar 

  16. Hartgerink JD, Beniash E, Stupp SI (2001) Self-assembly and mineralization of peptide-amphiphile nanofibers. Science 294:1684–1688

    Article  CAS  PubMed  Google Scholar 

  17. Sheng Y, Lin M, Li XW, Hao HX, Lin XY, Sun HC, Zhang H (2014) Enhancement of the 808 nm photothermal effect of gold nanorods by thiol-induced self-assembly. Part Syst Charact 31:788–793

    Article  CAS  Google Scholar 

  18. Liu TT, Chu MQ (2010) Stability of ‘quantum dot human epidermal growth factor’ bioconjugates prepared using quantum dots synthesised in aqueous solution. J Exp Nanosci 5:118–125

    Article  CAS  Google Scholar 

  19. Lee J, Zhou H, Lee J (2011) Small molecule induced self-assembly of Au nanoparticles. J Mater Chem 21:16935–16942

    Article  CAS  Google Scholar 

  20. Bian R, Wu X, Chai F, Li L, Zhang L, Wang T, Wang C, Su Z (2017) Facile preparation of fluorescent Au nanoclusters-based test papers for recyclable detection of Hg2+ and Pb2+. Sensors Actuators B Chem 241:592–600

    Article  CAS  Google Scholar 

  21. Gluhoi AC, Bogdanchikova N, Nieuwenhuys BE (2005) The effect of different types of additives on the catalytic activity of Au/Al2O3 in propene total oxidation: transition metal oxides and ceria. J Catal 229:154–162

    Article  CAS  Google Scholar 

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Acknowledgements

This work was supported by the National Natural Science Foundation of China (No.21076124 and No.51173104).

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Authors and Affiliations

  1. Engineering Research Center of Cell & Therapeutic Antibody, Ministry of Education, and School of Pharmacy, Shanghai Jiaotong University, 800 Dongchuan Road, Shanghai, 200240, China

    Wenli Zhu & Huili Li

  2. Institute of New Rural Development, Tong Ji University, Shanghai, 200092, China

    Ajun Wan

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  1. Wenli Zhu
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  2. Huili Li
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  3. Ajun Wan
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Correspondence to Huili Li.

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Zhu, W., Li, H. & Wan, A. EDC-Induced Self-Assembly of BSA-Au NCs. J Fluoresc 29, 627–630 (2019). https://doi.org/10.1007/s10895-019-02369-1

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