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Oligo(p-phenylene ethynylene) with Cyanoacrylate Terminal Groups and Graphene Composite as Fluorescent Chemical Sensor for Cysteine

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Abstract

A chemical sensor for cysteine (Cys) was fabricated based on a fluorescent oligo(p-phenylene ethynylene)s (OPEs) and OPE-graphene oxide (GO) composite. OPE with cyanoacrylate terminal groups were synthesized by a Pd-catalyzed Sonogashira coupling reaction and Knoevenagel condensation for use as a chemical sensor for Cys. The optical properties and Cys sensing capability of the cyanoacrylate modified OPE and OPE–GO composite were investigated. In addition of Cys, the fluorescence of OPE was blue-shifted and decreased (fluorescence turn-off), while the fluorescence of the OPE–GO composite was enhanced (fluorescence turn-on). Thus, OPE with cyanoacrylate terminal groups and OPE–GO composite acts a highly sensitive fluorescent chemical sensor for Cys.

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Acknowledgements

This work was partially supported by Research Institute for Science and Technology of Tokyo Denki University Grant Number Q15E-04, Japan.

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Authors and Affiliations

  1. Division of Science, School of Science and Engineering, Tokyo Denki University, Hatoyama, Hiki-gun, Saitama, 350-0394, Japan

    Naoya Adachi & Mariko Yoshinari

  2. Department of Science and Engineering, Graduate School of Science and Engineering, Tokyo Denki University, Hatoyama, Hiki-gun, Saitama, 350-0394, Japan

    Naoya Adachi, Eri Suzuki & Mari Okada

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  1. Naoya Adachi
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  2. Mariko Yoshinari
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Correspondence to Naoya Adachi.

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Adachi, N., Yoshinari, M., Suzuki, E. et al. Oligo(p-phenylene ethynylene) with Cyanoacrylate Terminal Groups and Graphene Composite as Fluorescent Chemical Sensor for Cysteine. J Fluoresc 27, 1449–1456 (2017). https://doi.org/10.1007/s10895-017-2084-4

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  • DOI: https://doi.org/10.1007/s10895-017-2084-4

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