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Liposomal Co-Encapsulation of Two Novel Europium Complexes and Doxorubicin: Fluorescence Study

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Abstract

The present study was undertaken to design the novel liposomal drug formulation containing doxorubicin and europium coordination complexes. It was shown that co-encapsulation of the drugs facilitates the partitioning and permeation of lanthanides into the lipid bilayer. The obtained results suggest that new drug platform may have potential application in the design of novel antitumor agents.

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Authors and Affiliations

  1. Department of Nuclear and Medical Physics, V.N. Karazin Kharkov National University, 4 Svobody Sq, Kharkov, 61072, Ukraine

    Valeriya M. Trusova & Galyna Gorbenko

  2. 19-32 Geroyev Truda Str, Kharkov, 61072, Ukraine

    Valeriya M. Trusova

  3. Department of Applied Organic Chemistry, Faculty of Chemistry, University of Sofia, 1164, Sofia, Bulgaria

    Todor Deligeorgiev

Authors
  1. Valeriya M. Trusova
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  2. Todor Deligeorgiev
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  3. Galyna Gorbenko
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Correspondence to Valeriya M. Trusova.

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Trusova, V.M., Deligeorgiev, T. & Gorbenko, G. Liposomal Co-Encapsulation of Two Novel Europium Complexes and Doxorubicin: Fluorescence Study. J Fluoresc 27, 1359–1363 (2017). https://doi.org/10.1007/s10895-017-2070-x

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  • DOI: https://doi.org/10.1007/s10895-017-2070-x

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