Skip to main content
Log in

Synthesis and Properties of a Novel FRET-Based Ratiometric Fluorescent Sensor for Cu2+

  • RAPID COMMUNICATION
  • Published:
Journal of Fluorescence Aims and scope Submit manuscript

Abstract

A novel FRET-based probe LS3 was designed and synthesized. As expected, it exhibited high selectivity and sensitivity for detecting Cu2+ over other commonly coexistent metal ions. The detection limit was measured to be 0.0423 μM for Cu2+, which can meet the selective requirements for practical application. In addition, the newly synthesized compound 3a/b have potential value of further synthesizing more analogous FRET-based probes.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Scheme 1
Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Scheme 2

References

  1. Xiao Y, Rowe AA, Plaxco KW (2007) J Am Chem Soc 129:262–263

    Article  CAS  PubMed  Google Scholar 

  2. Han R, Yang X, Zhang D, Fan M, Ye Y, Zhao Y (2012) New J Chem 36:1961–1965

    Article  CAS  Google Scholar 

  3. Wu P, Li Y, Yan XP (2009) Anal Chem 81:6252–6257

    Article  CAS  Google Scholar 

  4. Kabehie S, Xue M, Stieg AZ, Liong M, Wang KL (2010) J Am Chem Soc 132:15987–15996

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Fan LJ, Zhang Y, Murphy CB, Angell SE, Parker MFL, Flynn BR, Jones WE (2009) Coord Chem Rev 253:410–422

    Article  CAS  Google Scholar 

  6. Wang J, Zhang D, Liu Y, Ding P, Wang C, Ye Y, Zhao Y (2014) Sensor Actuat B-Chem 191:344–350

    Article  CAS  Google Scholar 

  7. Valeur B, Leray I (2000) Coord Chem Rev 205:3–40

    Article  CAS  Google Scholar 

  8. Linder MC, Hazegh Azam M (1996) Am J Clin Nutr 63:797–811

    Google Scholar 

  9. Waggoner DJ, Bartnikas TB, Gitlin JD (1999) Neurobiol Dis 6:221–230

    Article  CAS  PubMed  Google Scholar 

  10. Bruijn LI, Miller TM, Cleveland DW (2004) Annu Rev Neurosci 27:723–749

    Article  CAS  PubMed  Google Scholar 

  11. Barnham KJ, Masters CL, Bush AI (2004) Nat Rev Drug Discov 3:205–214

    Article  CAS  PubMed  Google Scholar 

  12. Du J, Wang H (2010) Org Lett 12:476–479

    Article  CAS  PubMed  Google Scholar 

  13. Kim S, Yoon Y (2009) Org Lett 11:4442–4445

    Article  PubMed  Google Scholar 

  14. Kim S (2010) Org Lett 12:3852–3855

    Article  PubMed  Google Scholar 

  15. Zhang X, Yu R (2009) Anal Chem 81:7022–7030

    Article  PubMed  Google Scholar 

  16. Fan JL, Sun W, Hu MM, Cao JF, Cheng GH, Dong HJ, Song KD, Liu YC, Sun SG, Peng XJ (2012) Chem Commun 48:8117–8119

    Article  CAS  Google Scholar 

  17. Lin WY, Long LL, Yuan L, Cao ZM, Feng JB (2009) Anal Chim Acta 634:262–266

    Article  CAS  PubMed  Google Scholar 

  18. Lee MH, Kim HJ (2008) Yoon S, et al. Org Lett 10:213–216

    Article  CAS  PubMed  Google Scholar 

  19. Yuan L, Lin W, Xie Y, et al. (2011) Chem Commun 47:9372–9374

    Article  CAS  Google Scholar 

  20. Liu YL, Lv X, Zhao Y, et al. (2012) Dyes Pigments 92:909–915

    Article  CAS  Google Scholar 

  21. Zhou Y, Zhang J, Zhang L, Zhang Q, Ma T, Niu J (2013) Dyes and Pigments. 97:148–154

    Article  CAS  Google Scholar 

  22. Liu D, Pang T, Ma K, Jiang W, Bao X (2014) RSC Adv 4:2563–2567

    Article  CAS  Google Scholar 

  23. Klassen CD (1995) The basic science of poisons, fifth edn. McGraw-Hill, New York, p. 715

    Google Scholar 

  24. Standardization Administration of the People’s Republic of China, Standard examination methods for drinking water–metal parameters, GB/T 5750.6-2006.

  25. Xiang Y, Tong AJ, Jin PY, Ju Y (2006) Org Lett 8:2863–2866

    Article  CAS  PubMed  Google Scholar 

  26. Huo FJ, Su Y, Sun Q, Yin CX, Tong HB, Nie ZX (2010) Dyes Pigment 86:50–55.

    Article  CAS  Google Scholar 

  27. Xiang Y, Li ZF, Chen XT, Tong AJ (2008) Talanta 74:1148–1153

    Article  CAS  PubMed  Google Scholar 

  28. Zhang D, Zou R, Wang M, Chai M, Wang X, Ye Y, Zhao Y (2013) J Fluoresc 23:13–19

    Article  PubMed  Google Scholar 

  29. Guan X, Lin W, Huang W (2014) Org Biomol Chem 12:3944–3949

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgment

This work was supported by the National Science Foundation of China (Nos. 21572209, 21442002), Project of unknown hazards factor identification and the known hazard factor safety assessment for products of edible mushrooms (GJFP2015006), Science-Technology Foundation for Outstanding Young Scientists of Henan Academy of Agricultural Sciences (Grant no. 2013YQ24 and 2016YQ22).

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Jihong Liu or Yong Ye.

Electronic supplementary material

ESM 1

(DOC 2.33 mb)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Li, S., Zhang, D., Wang, M. et al. Synthesis and Properties of a Novel FRET-Based Ratiometric Fluorescent Sensor for Cu2+ . J Fluoresc 26, 769–774 (2016). https://doi.org/10.1007/s10895-016-1768-5

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10895-016-1768-5

Keywords

Navigation