Skip to main content
Log in

A Sensitive and Selective Fluorescent Coumarin-Based Probe for Detection of Hypochlorite ion and its Application to Cellular Imaging

  • ORIGINAL ARTICLE
  • Published:
Journal of Fluorescence Aims and scope Submit manuscript

Abstract

Selective, sensitive fluorescent probes for ClO are desirable due to the importance of ClO in biological processes. Herein, a readily available turn-off fluorescent probe for ClO is reported, which displays highly selectivity and sensitivity over other common anions and reactive oxygen/nitrogen. Moreover, it is able to detect ClO in Ramos cells via cellular imaging.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7

Similar content being viewed by others

References

  1. Yap YW, Whiteman M, Cheung NS (2007) Cell Signal 19:219

    Article  CAS  PubMed  Google Scholar 

  2. Ramsey MR, Sharpless NE (2006) Nat Cell Biol 8:1213

    Article  CAS  PubMed  Google Scholar 

  3. Zavodnik LB, Zavodnik IB, Lapshyna EA, Buko VU, Bryszewska MJ (2002) Bio-Electrochemistry 58:157

    CAS  Google Scholar 

  4. Nussbaum C, Klinke A, Adam M, Baldus S, Sperandio M (2013) Antioxid Redox Signaling 18:692

    Article  CAS  Google Scholar 

  5. Liu BY, Hou XR, Zhou QG, Tian JW, Zhu P, Xu J, Hou FF, Fu F (2001) Free Radic Res 45:662

    Article  Google Scholar 

  6. de Silva AP, Gunaratne HQN, Gunnlaugsson T, Huxley AJM, McCoy CP, Rademacher JT, Rice TE (1997) Chem Rev 97:1515

    Article  PubMed  Google Scholar 

  7. Yang Y, Zhao Q, Feng W, Li F (2013) Chem Rev 113:192

    Article  CAS  PubMed  Google Scholar 

  8. Chen X, Pradhan T, Wang F, Kim JS, Yoon J (2012) Chem Rev 112:1910

    Article  CAS  PubMed  Google Scholar 

  9. Kenmoku S, Urano Y, Kojima H, Nagano T (2007) J Am Chem Soc 129:7313

    Article  CAS  PubMed  Google Scholar 

  10. Koide Y, Urano Y, Hanaoka K, Terai T, Nagano T (2011) J Am Chem Soc 133:5680

    Article  CAS  PubMed  Google Scholar 

  11. Chen X, Wang X, Wang S, Shi W, Wang K, Ma H (2008) Chem Eur J 14:4719

    Article  CAS  PubMed  Google Scholar 

  12. Xie XL, Chen XP, Li B, Zhang LM (2013) Dyes Pigments 98:422

    Article  CAS  Google Scholar 

  13. Lou XD, Zhang Y, Li QQ, Qin JG, Li Z (2011) Chem Commun 47:3189

    Article  CAS  Google Scholar 

  14. Cui K, Zhang DQ, Zhang GX, Zhu DB (2010) Tetrahedron Lett 51:6052

    Article  CAS  Google Scholar 

  15. Xu QL, Lee K, Lee S, Lee KM, Lee W, Yoon J (2013) J Am Chem Soc 135:9944

    Article  CAS  PubMed  Google Scholar 

  16. Chen X, Lee KA, Ha EM, Lee KM, Seo YY, Choi HK, Kim NH, Kim MJ, Cho CS, Lee SY, Lee WJ, Yoon J (2011) Chem Commun 47:4373

    Article  CAS  Google Scholar 

  17. Wu XJ, Li Z, Yang L, Han JH, Han SF (2013) Chem Sci 4:460

    Article  CAS  Google Scholar 

  18. Cheng X, Jia H, Long T, Feng J, Qin J, Li Z (2011) Chem Commun 47:11978

    Article  CAS  Google Scholar 

  19. Chen S, Lu J, Sun C, Ma H (2010) Analyst 135:577

    Article  CAS  PubMed  Google Scholar 

  20. Goswami S, Paul S, Manna A (2013) Dalton Trans 42:10097

    Article  CAS  PubMed  Google Scholar 

  21. Goswami S, Manna A, Paul S, Kheng QC, Fun H (2013) Chem Commun 49:11656

    Article  CAS  Google Scholar 

  22. Yuan L, Lin W, Song J, Yang Y (2011) Chem Commun 47:12691

    Article  CAS  Google Scholar 

  23. Liu F, Wu T, Cao J, Zhang H, Hu M, Sun S, Song F, Fan J, Wang J, Peng X (2013) Analyst 138:775

    Article  CAS  PubMed  Google Scholar 

  24. Guo T, Cui L, Shen J, Wang R, Zhu W, Xu Y, Qian X (2013) Chem Commun 49:1862

    Article  CAS  Google Scholar 

  25. Hu ZQ, Sun LL, Gu YY, Jiang Y (2015) Sensors Actuators B Chem 212:220

    Article  CAS  Google Scholar 

  26. Jung HS, Kwon PS, Lee JW, Kim JI, Hong CS, Kim JW, Yan S, Lee JY, Lee JH, Joo T, Kim JS (2009) J Am Chem Soc 131:2008

    Article  CAS  PubMed  Google Scholar 

  27. Ezeh VC, Harrop TC (2013) Inorg Chem 52:2323

    Article  CAS  PubMed  Google Scholar 

  28. Sun Y, Liu J, Zhang J, Yang T, Guo W (2013) Chem Commun 49:2637

    Article  CAS  Google Scholar 

  29. Inoue M, Nishikawa M, Kasahara E, Sato E (1999) Mech Aging Dev 11:89

    Article  Google Scholar 

  30. Hagen H, Marzenell P, Jentzsch E, Wenz F, Veldwijk MR, Mokhir A (2012) J Med Chem 55:924

    Article  CAS  PubMed  Google Scholar 

  31. Kim S, Noh JY, Kim KY, Kim JH, Kang HK, Nam SW, Kim SH, Park S, Kim C, Kim J (2012) Inorg Chem 51:3597

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgments

The authors are grateful for the financial support from National Natural Science Foundation of China for the Youth (21202180).

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Hui-Li Gong or Yi Jiang.

Electronic supplementary material

ESM 1

(DOCX 257 kb)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Gong, HL., Jiang, Y., Hou, RC. et al. A Sensitive and Selective Fluorescent Coumarin-Based Probe for Detection of Hypochlorite ion and its Application to Cellular Imaging. J Fluoresc 26, 403–406 (2016). https://doi.org/10.1007/s10895-015-1726-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10895-015-1726-7

Keywords

Navigation