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A Rhodamine-Benzimidazole Based Chemosensor for Fe3+ and its Application in Living Cells

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Abstract

A rhodamine-benzimidazole based chemosensor was designed and prepared for Fe3+ via opening of the spiro-ring to give fluorescent and colored species. L exhibited high selectivity and excellent sensitivity in both absorbance and fluorescence detection of Fe3+ in aqueous solution with comparatively wide pH range (5.8–7.4). The detection limit of this newly developed probe was shown to be up to 2.74 μM. The reversibility establishes the potential of both probes as chemosensors for Fe3+ detection. Fluorescence imaging experiments of Fe3+ in living MGC803 cells demonstrated its value of practical applications in biological systems.

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Acknowledgments

This work was supported by the National Science Foundation of China (Nos. 21572209) and Program for New Century Excellent Talents in University (NCET-11- 0950).

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Authors and Affiliations

  1. School of Chemistry and Chemical Engineering, Xuchang University, Xuchang, 461000, China

    Gongchun Li

  2. Phosphorus Chemical Engineering Research Center of Henan Province, The College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, 450052, China

    Jun Tang, Peigang Ding & Yong Ye

Authors
  1. Gongchun Li
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  2. Jun Tang
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  3. Peigang Ding
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  4. Yong Ye
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Corresponding author

Correspondence to Yong Ye.

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Li, G., Tang, J., Ding, P. et al. A Rhodamine-Benzimidazole Based Chemosensor for Fe3+ and its Application in Living Cells. J Fluoresc 26, 155–161 (2016). https://doi.org/10.1007/s10895-015-1696-9

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  • DOI: https://doi.org/10.1007/s10895-015-1696-9

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