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Cilostazol Determination by the Enhancement of the Green Emission of Tb3+ Optical Sensor

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Abstract

The efficiency of excited-state interaction between Tb3+ and the industrial product Cilostazol (CIL) has been studied in different solvents. High luminescence intensity peak at 545 nm of terbium complex in acetonitrile was obtained. The photophysical properties of the green emissive Tb3+ complex have been elucidated, the terbium was used as optical sensor for the assessment of CIL in the pharmaceutical tablets and body fluids at pH 3.1 and λex = 320 nm with a concentration range 1.0 × 10−9–1.0 × 10−6 mol L−1 of CIL, correlation coefficient of 0.998 and detection limit of 7.5 × 10−10 mol L−1.

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Authors and Affiliations

  1. Department of Chemistry, Faculty of Science, Ain Shams University, Cairo, Egypt

    M. S. Attia, A. O. Youssef & M. S. Mostafa

  2. Chemistry Department, Faculty of Applied Science, Taibah University, Al-Madinah Al-Munawarah, Kingdom of Saudi Arabia

    W. H. Mahmoud

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  1. M. S. Attia
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  2. W. H. Mahmoud
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  3. A. O. Youssef
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  4. M. S. Mostafa
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Correspondence to M. S. Attia.

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Attia, M.S., Mahmoud, W.H., Youssef, A.O. et al. Cilostazol Determination by the Enhancement of the Green Emission of Tb3+ Optical Sensor. J Fluoresc 21, 2229–2235 (2011). https://doi.org/10.1007/s10895-011-0927-y

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  • DOI: https://doi.org/10.1007/s10895-011-0927-y

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