The objectives of this study were to assess the prevalence of personality disorders and to examine personality as a predictor of psychosocial characteristics and behaviors of HCV patients. HCV patients (n = 259) from three infectious disease and liver clinics who completed Cloninger’s Temperament and Character Inventory (TCI), an inventory for personality traits, were included in the study. Patients with low scale scores in the character dimension of both cooperativeness and self-directedness (low CO/SD) were defined as having a personality disorder. Using low CO/SD in combination with demographic, psychiatric/substance use, and HCV-related variables, linear regression was used to construct separate models of risky behaviors, quality of life, functioning, burden of illness, and social support. The prevalence of low CO/SD was high in this sample of HCV patients. Low CO/SD was an independent predictor of risky behaviors, quality of life, functioning, and social support.
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Conflict of interest
This work was supported by a National Institute on Alcohol Abuse and Alcoholism Grant R01 AA15201 to Dr. North. The research reported in this publication was supported by the National Institute on Drug Abuse of the National Institutes of Health under award R25DA028567 to Dr. Sims. Drs. Oh, Pollio, Hong, and Pollio do not have any conflict of interest to disclose.
Research Involving Human Participants and/or Animals
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee (include the name of committee + reference number) and with the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards. This article does not contain any studies with animals performed by any of the authors.
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Sims, O.T., Oh, H., Pollio, D.E. et al. Personality in Combination with Alcohol and Drug Use and Psychiatric Disorders to Predict Psychosocial Characteristics and Behaviors of Hepatitis C Patients. J Clin Psychol Med Settings 28, 161–167 (2021). https://doi.org/10.1007/s10880-019-09694-4
- Hepatitis C
- Alcohol use
- Drug use