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Extravascular leakage of induction doses of rocuronium: four cases in which both depth of neuromuscular block and plasma concentration of rocuronium were assessed

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Abstract

The duration of action of extravasated rocuronium varies depending on the patient’s comorbidities. In patients who receive high doses of non-depolarizing neuromuscular blocking agents subcutaneously, anesthesiologists should be aware of unexpected prolongation of the progress and recovery of neuromuscular block. In such cases, the depth and recovery of neuromuscular block should be objectively monitored to avoid residual neuromuscular block and recurarization.

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Funding

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Author notes

  1. Shunichi Takagi and Miho Kijima contributed equally as first authors.

Authors and Affiliations

  1. Department of Anesthesiology, Nihon University School of Medicine, 30-1, Oyaguchi Kamimachi, Itabashi-Ku, Tokyo, 173-8610, Japan

    Shunichi Takagi, Miho Kijima, Hajime Iwasaki, Akira Doshu-Kajiura, Osamu Kitajima & Takahiro Suzuki

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  1. Shunichi Takagi
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  2. Miho Kijima
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  3. Hajime Iwasaki
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  4. Akira Doshu-Kajiura
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  5. Osamu Kitajima
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  6. Takahiro Suzuki
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Contributions

Data collection: ST, MK, HI, AD-K, OK, Data analysis: all authors, Writing manuscript: ST, MK, Review and editing: all authors.

Corresponding author

Correspondence to Takahiro Suzuki.

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Conflict of interest

Takagi S, Iwasaki H and Suzuki T have received speaker fees from MSD Inc., JAPAN.

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Written informed consent was obtained from all the patients or their close relatives.

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Patients signed informed consent regarding publishing their data.

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Takagi, S., Kijima, M., Iwasaki, H. et al. Extravascular leakage of induction doses of rocuronium: four cases in which both depth of neuromuscular block and plasma concentration of rocuronium were assessed. J Clin Monit Comput 36, 587–592 (2022). https://doi.org/10.1007/s10877-021-00692-2

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  • DOI: https://doi.org/10.1007/s10877-021-00692-2

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