A novel non-invasive blood pressure waveform measuring system compared to Millar applanation tonometry

  • Sándor Földi
  • Tamás Horváth
  • Flóra Zieger
  • Péter Sótonyi
  • György Cserey
Original Research
  • 107 Downloads

Abstract

The accurate, non-invasive, measuring of the continuous arterial blood pressure waveform faces some difficulties and an innovative blood pressure measurement technology is urgently needed. However, the arterial blood pressure waveform plays an essential role in health care by providing diagnostic information and base for calculating several heart function parameters. The aim of this study is to introduce a novel non-invasive measuring system that can measure the arterial blood pressure waveform with high accuracy in comparison to an applanation tonometry system. The applied measuring device utilizes a new measurement strategy enabled by the OptoForce 3D force sensor, which is attached to the wrist at the radial artery. To validate the accuracy, 30 simultaneous measurements were taken with a Millar tonometer. For the simultaneously recorded non-invasive signals, the similarity was high (the average correlation was \(0.9213\pm 0.063\)). The differences in the systolic and the diastolic blood pressure measured by the two systems are small. The average differences (\(\pm \hbox {SD}\)) for simultaneously recorded systolic, diastolic, mean arterial and incisura pressures were: \(0.35\pm 1.75\), \(0.02 \pm 0.19\), \(2.88\pm 2.42\) and \(3.84\pm 3.90 \,\text {mmHg}\), respectively. These results satisfy the AAMI criteria. Based on our results, this new system requires further development and validation against invasive arterial blood pressure monitoring in order to prove its usefulness in patient monitoring, emergency care, and pulse diagnosis.

Keywords

Continuous blood pressure Applanation tonometry Patient monitoring Arterial pressure 

Notes

Acknowledgements

This research was supported by Pázmány Péter Catholic University (KAP-1.1-14/017, KAP15-058-1.1-ITK and KAP16-71045-1.1-ITK). We are also grateful for the support of the Roska Tamás Doctoral School of Science and Technology at the Faculty of Information Technology and Bionics (ITK - Research Faculty) of Pázmány Péter Catholic University (PPCU - University of National Excellence) as well as the technical assistance provided by OptoForce Ltd. and the MTA-SE Cardiovascular Imaging Research Group led by Dr. Pál Maurovich-Horvat. Tamás Horváth was sponsored by NKFIH postdoctoral program, grant number: PD 121186. The research has been partially supported by the European Union, co-financed by the European Social Fund (EFOP-3.6.3-VEKOP-16-2017-00002).

Compliance with ethical standards

Conflict of interest

None of the authors has any conflicts of interest to disclose. All authors approved the current version of the manuscript for publication.

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Copyright information

© Springer Science+Business Media B.V. 2017

Authors and Affiliations

  1. 1.Faculty of Information Technology and BionicsPázmány Péter Catholic UniversityBudapestHungary
  2. 2.Department of Vascular SurgerySemmelweis UniversityBudapestHungary
  3. 3.Department of Hydrodynamic Systems, Faculty of Mechanical EngineeringBudapest University of Technology and EconomicsBudapestHungary

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