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Continuous-wave near-infrared spectroscopy is not related to brain tissue oxygen tension

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Abstract

Near-infrared spectroscopy (NIRS) has gained acceptance for cerebral monitoring, especially during cardiac surgery, though there are few data showing its validity. We therefore aimed to correlate invasive brain tissue oxygen measurements (PtiO2) with the corresponding NIRS-values (regional oxygen saturation, rSO2). We also studied whether NIRS was able to detect ischemic events, defined as a PtiO2-value of <15 mmHg. Eleven patients were studied with invasive brain tissue oxygen monitoring and continuous-wave NIRS. PtiO2-correlation with corresponding NIRS-values was calculated. We found no correlation between PtiO2- and NIRS-readings. Measurement of rSO2 was no better than flipping a coin in the detection of cerebral ischemia when a commonly agreed ischemic PtiO2 cut-off value of <15 mmHg was chosen. Continuous-wave-NIRS was unable to reliably detect ischemic cerebral episodes, defined as a PtiO2 value <15 mmHg. Displayed NIRS-values did not correlate with invasively measured PtiO2-values. CW-NIRS should not be used for the detection of cerebral ischemia.

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Author information

Authors and Affiliations

  1. Department of Neurosurgery, University Medical Center, Johannes Gutenberg University, Langenbeckstr. 1, 55131, Mainz, Germany

    Thomas Kerz, Christian Beyer, Darius Kalasauskas, Amr Nimer Amr & Stefan Welschehold

  2. University Medical Center, Institute of Neuroradiology, Johannes Gutenberg University, Mainz, Germany

    Stephan Boor

  3. Ludmillenstift, Meppen, Germany

    Alexandra Huthmann

Authors
  1. Thomas Kerz
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  2. Christian Beyer
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  3. Alexandra Huthmann
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Corresponding author

Correspondence to Thomas Kerz.

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Ethical standard

The protocol for this study has been approved by the local ethics committee (Ethikkommission der Landesaerztekammer Rheinland-Pfalz). Upon hospitalization, all patients or their proxies agree to the use of their anonymized data for scientific purposes by signing the admission contract. Individual patient consent was not required for this study. The study was performed in compliance with the Helsinki Declaration.

Funding and conflict of interest

There has been no funding for this study. We have no conflicts of interest to report.

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Kerz, T., Beyer, C., Huthmann, A. et al. Continuous-wave near-infrared spectroscopy is not related to brain tissue oxygen tension. J Clin Monit Comput 30, 641–647 (2016). https://doi.org/10.1007/s10877-015-9755-y

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  • DOI: https://doi.org/10.1007/s10877-015-9755-y

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