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Closed loop mechanical ventilation

Abstract

Mechanical ventilation is a sophisticated technique with very narrow therapeutic ranges i.e. highly efficient and able to keep alive the most severe patients, but with considerable side effects and unwanted complications if not properly and timely used. Computerized protocols, closed loop systems, decision support, all terms which need to be defined, may help making mechanical ventilation safer and more efficient. The present paper will provide a short overview on technical and engineering considerations regarding closed loop controlled ventilation as well as tangible clinical evidences supporting the previous statement.

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Conflict of interest

Dr. M. Wysocki is medical director for GE Healthcare, Life Care Solution Europe and he is co-sharing several patents related to IntelliVent™ which is a product of Hamilton Medical where he was formerly Head of Medical Research and Innovation; Dr. P. Jouvet holds a clinical research scholarship from FRSQ (Fonds de Recherche en Santé du Québec). A S1 respirator was provided for research purposes by Hamilton Medical. P.J. was invited twice to present the results of a clinical research on IntelliVent® at international meetings organised by Hamilton Medical without any honoraria. P.J. also has a respirator Servo-i and an Evita XL, provided for research purposes by Maquet Medical (Solna, Sweden) and Dräger Medical (Lübeck, Germany), respectively. P.J.’s research on clinical decision support systems is funded by a public grant from the Natural Sciences and Engineering Research Council of Canada; and Dr. S. Jaber runs a laboratory that has received research grants for specific research projects from Dräger-France, Maquet-France and Fisher-Paykel-France: None.

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Correspondence to Marc Wysocki.

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Wysocki, M., Jouvet, P. & Jaber, S. Closed loop mechanical ventilation. J Clin Monit Comput 28, 49–56 (2014). https://doi.org/10.1007/s10877-013-9465-2

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  • DOI: https://doi.org/10.1007/s10877-013-9465-2

Keywords

  • Mechanical ventilation
  • Closed loop mechanical ventilation
  • Critical care medicine
  • Clinical trials
  • Graphic user interface