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Multicenter Evaluation of Noninvasive Cardiac Output Measurement by Bioreactance Technique

Journal of Clinical Monitoring and Computing volume 22, pages 113–119 (2008)Cite this article

Abstract

Objectives

Bioreactance, the analysis of intrabeat variations in phase of a transthoracic voltage in response to an applied high frequency transthoracic current, was recently introduced for noninvasive cardiac output measurement (NICOM). We evaluated NICOM compared to thermo- dilution (TD) in several clinical settings.

Methods

111 patients with a clinical indication for TD cardiac output (CO) measurement were recruited at five centers, including patients in cardiac catheterization laboratories, cardiac care units and intensive care units. CO measurements were made simulta- neously with TD and the bioreactance method and compared by regression analysis.

Results

For studies in the intensive care units, TD-based CO and NICOM were highly correlated (r = 0.78, P < 0.0001) and did not differ significantly from each other (P = 0.55). Results in the cardiac catheterization laboratory were similar (r = 0.71, P < 0.001; P = 0.28 NICOM versus TD). In subsets of patients, NICOM was shown to be better corre- lated with TD-CO than CO obtained with the Fick method or with standard bioimpedance-based measurements of CO.

Conclusions

On average, compared to TD, bioreactance- based NICOM has acceptable accuracy in challenging clinical environments. Availability of such a tool may allow clinicians to have information about CO in patients where this information is not currently available to help diagnosis and guide therapy.

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Author information

Affiliations

  1. Atlanta Cardiology Group, 5665 Peachtree Dunwoody Road, Suite 172, Atlanta, GA, 30342, USA

    Nirav Y. Raval MD

  2. Clinique Ambroise Pare, Neuilly, Paris, France

    Pierre Squara MD

  3. Yale University, New Haven, CT, USA

    Michael Cleman MD

  4. Northwest Texas Hospital, Amarillo, TX, USA

    Kishore Yalamanchili MD

  5. Klinikum Traunstein, Traunstein, Germany

    Michael Winklmaier MD

  6. Columbia University, New York, NY, USA

    Daniel Burkhoff MD PhD

Authors
  1. Nirav Y. Raval MD
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  2. Pierre Squara MD
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  3. Michael Cleman MD
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  4. Kishore Yalamanchili MD
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  5. Michael Winklmaier MD
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  6. Daniel Burkhoff MD PhD
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Corresponding author

Correspondence to Nirav Y. Raval MD.

Additional information

Raval NY, Squara P, Cleman M, Yalamanchili K, Winklmaier M, Burkhoff D. Multicenter evaluation of noninvasive cardiac output measurement by bioreactance technique.

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Raval, N.Y., Squara, P., Cleman, M. et al. Multicenter Evaluation of Noninvasive Cardiac Output Measurement by Bioreactance Technique. J Clin Monit Comput 22, 113–119 (2008). https://doi.org/10.1007/s10877-008-9112-5

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  • DOI: https://doi.org/10.1007/s10877-008-9112-5

Keywords

  • non-invasive monitoring
  • cardiac output
  • bioimpedance
  • bioreactance