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RETRACTED ARTICLE: Treatment Activity of Co(II) Complexes on Osteoarthritis Induced by Anterior Ligament Reconstruction by Inhibiting the nf-κb Signaling Pathway

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This article was retracted on 30 January 2024

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Abstract

Two metal–organic coordination complexes whose chemical formulae were [Co2(Htpt)2(H2O)2]·CH3CN}n (1) and [Co(H2tpt)2]·3H2O (2) based on the polydentate 4-(2,4,6-tricarboxyphenyl)-2,2′,6,2″-terpyridine ligand (H3tpt) have been synthesized using a hydrothermal reaction method, and their structures were determined via a series of characterization methods. The as-prepared coordination complexes were studied via single-crystal X-ray diffraction, powder X-ray diffraction, elemental analysis, and thermogravimetric analysis. Structural analysis revealed that complex 1 has a 2D-layered structure with a (3,3)-linked hcb network, while complex 2 features discrete structure, which is further extended into a 3D supramolecular network via H-bond interactions. Their treatment activity on osteoarthritis induced by anterior ligament reconstruction was evaluated. First, the inflammatory response in the bone joint was assessed using an enzyme-linked immunosorbent assay detection kit. The activation of the nf-κb signaling routine at the bone joint was assessed using real-time reverse transcription polymerase chain reaction.

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Authors and Affiliations

  1. Department of Clinical Laboratory, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China

    Wei Jiang & Shanshan Liang

  2. Department of Urology, Tangdu Hospital, The Air Force Medical University, Xi’an, Shaanxi, China

    Xiaoye Jiang

  3. Department of Medicine, Inner Mongolia Hospital, Bayannur, Inner Mongolia, China

    Yuan Ma & Yonggang Wu

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  1. Wei Jiang
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  2. Shanshan Liang
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  3. Xiaoye Jiang
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  4. Yuan Ma
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  5. Yonggang Wu
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Correspondence to Shanshan Liang.

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This article has been retracted. Please see the retraction notice for more detail: https://doi.org/10.1007/s10876-024-02563-7"

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Jiang, W., Liang, S., Jiang, X. et al. RETRACTED ARTICLE: Treatment Activity of Co(II) Complexes on Osteoarthritis Induced by Anterior Ligament Reconstruction by Inhibiting the nf-κb Signaling Pathway. J Clust Sci 33, 1773–1779 (2022). https://doi.org/10.1007/s10876-021-02105-5

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  • DOI: https://doi.org/10.1007/s10876-021-02105-5

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