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RETRACTED ARTICLE: Multifunctional Zinc Metal–Organic Framework for Highly Selective Detection of Picric Acid and Inhibition of Laryngeal Cancer Cell Growth

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This article was retracted on 31 January 2024

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Abstract

A new rigid and symmetrical tetracarboxylic ligand 2,3,5,6-tetrakis(4-carboxyphenyl)pyrazine (H4TCPP) ligand was employed in the construction of a new Zn(II)-based metal–organic framework [Zn3(OH)2(H2TCPP)2](DMF)3 (1). Complex 1 not only displays bright blue luminescence arising from the matrix coordination-induced emission effect of the TCPP2− ligand, but also exhibits effective detection for picric acid in the solution with the quenching constant of 3.59 × 104 M−1. In the biological study, we investigated the effect of compound on Hep laryngeal cancer cell viability and proliferation with CCK8 assay, analyzed the production of autophagy in Hep cells by flow cytometer, and the western blot was also used to detect the expression of autophagy-related proteins. Moreover, the autophagy inhibitor 3-MA was used in this study to explore the role of autophagy in the anti-cancer activity of compound.

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Authors and Affiliations

  1. Department of Otolaryngology, TEDA Hospital, Tianjin, 300457, China

    Wen-Kui Wu & Jia-Liang Guo

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  1. Wen-Kui Wu
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  2. Jia-Liang Guo
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Correspondence to Wen-Kui Wu.

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This article has been retracted. Please see the retraction notice for more detail: https://doi.org/10.1007/s10876-024-02549-5"

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Wu, WK., Guo, JL. RETRACTED ARTICLE: Multifunctional Zinc Metal–Organic Framework for Highly Selective Detection of Picric Acid and Inhibition of Laryngeal Cancer Cell Growth. J Clust Sci 31, 435–443 (2020). https://doi.org/10.1007/s10876-019-01657-x

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  • DOI: https://doi.org/10.1007/s10876-019-01657-x

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