Abstract
Nanosized F-substituted hydroxyapatite (FA; Ca10(PO4)6(OH)2 − xFx) was synthesized with CaCO3, P2O5 and CaF2 as a precursor via a mechanochemical process. Different times of milling (10 min, 2, 4, 6, 8, 10, 12 and 14 h) and fluorine ion contents (0, 25, 50, 75 and 100 percent of substitution) were used to prepare the products. Transmission electron microscopy (TEM) analysis demonstrated that FA nanoparticles with an average diameter of 15–30 nm (at milling time of 10 h) were prepared. Finally, the bioactivity of optimal samples was investigated in simulated body fluid (SBF).
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R. Z. Le Geros and J. P. Le Geros Dense hydroxyapatite. in L. L. Hench and J. Wilson (eds.), Introduction to bioceramics (World Scientific, Singapore, 1993).
Y. Chen and X. Miao (2004). Ceram. Int. 30, 1961–1965.
C. Shu, W. Yanwei, L. Hong, P. Zhengzheng, and Y. Kangde (2005). Ceram. Int. 31, 135.
M. H. Fathi, E. MohammadiZahrani, and A. Zomorodian (2009). Mater. Lett. 63, 1195–1198.
M. H. Fathi and E. MohammadiZahrani (2009). J. Cryst. Growth 311, 1392–1403.
M. Kheradmandfard and M. H. Fathi (2010). J. Alloys Compd. 504, 141–145.
A. Bianco, I. Cacciotti, M. Lombardi, L. Montanaro, E. Bemporad, and M. Sebastiani (2010). Ceram. Int. 36, 313–322.
M. Kheradmandfard, M. H. Fathi, M. Ahangarian, and E. MohammadiZahrani (2012). Ceram. Int. 38, 169–175.
W. Suchanek, K. Byrappa, P. Shuk, R. E. Riman, V. F. Janas, and K. S. TenHuisen (2004). Biomaterials 25, 4647–4657.
S. Kannan, J. H. G. Rocha, S. Agathopoulos, and J. M. F. Ferreira (2007). Acta Biomater. 3, 243–249.
G. K. Williamson and W. H. Hall (1953). X-ray line broadening from filed aluminium and wolfram. Acta Metall. 1, 22–31.
E. Landi, A. Tampieri, G. Celotti, and S. Sprio (2000). J. Eur. Ceram. Soc. 20, 2377–2387.
T. J. Webster, E. A. Massa-Schlueter, J. L. Smith, and E. B. Slamovich (2004). Biomaterials 25, 2111–2121.
M. Bohner and J. Lemaitre (2009). Can bioactivity be tested in vitro with SBF solution. Biomaterials 30, 2175–2179.
M. H. Fathi and E. Mohammadi Zahrani (2009). J. Alloys Compd. 475, 408–414.
L. M. Rodriguez-Lorenzo, J. N. Hart, and K. A. Gross (2003). Biomaterials 24, 3777–3785.
C. Suryanarayana (2001). Mechanical alloying and milling. Prog. Mater. Sci. 46, 1–184.
Y. Chen and X. Miao (2005). Biomaterials 26, 1205–1210.
K. Cheng, W. Weng, H. Wang, and S. Zhang (2005). Biomaterials 26, 6288–6295.
M. Tatzber, M. Stemmer, H. Spiegel, C. Katzlberger, G. Haberhauer, and M. H. Gerzabek (2007). Environ. Chem. Lett. 5, 9–12.
A. Eisazadeh, K. A. Kassim, and H. Nur (2010). J. Geotech. Eng. 15 D 1–10.
B. Boonchom and C. Danvirutai (2009). J. Optoelectron. Biomed. Mat. 1, 115–123.
S. C. Liou and S. Y. Chen (2002). Biomaterials 23, 4541–4547.
A. Bigi, E. Boanini, C. Capuccini, and M. Gazzano (2007). Inorg. Chim. Acta 360, 1009–1016.
S. Z. Liuming Yan, D. Zhang, and Q. Feng (2011). Polymer 52, 881–892.
J. M. Hughes, M. Cemeron, and K. D. Crawley (1989). Am. Miner. 74, 870–876.
C. C. Silva, D. Thomazini, A. G. Pinheiro, F. Lanciotti Jr, J. M. Sasaki, J. C. Goes, and A. S. B. Sombra (2002). J. Phys. Chem. Solids 63, 1745–1757.
M.-X. Zhang and G.-J. Zhao (2012). ChemSusChem 5, 879–887.
G.-J. Zhao, J.-Y. Liu, L.-C. Zhou, and K.-L. Han (2007). J. Phys. Chem. B 111, 8940–8945.
G.-J. Zhao, B. H. Northrop, K.-L. Han, and P. J. Stang (2010). J. Phys. Chem. A 114, 9007–9013.
G.-J. Zhao and K.-L. Han (2012). Acc. Chem. Res. 45, 404–413.
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Fereshteh, Z., Fathi, M. & Mozaffarinia, R. Synthesis and Characterization of Fluorapatite Nanoparticles Via a Mechanochemical Method. J Clust Sci 26, 1041–1053 (2015). https://doi.org/10.1007/s10876-014-0793-2
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DOI: https://doi.org/10.1007/s10876-014-0793-2